BC recreational fisheries: exploring potential for development of kokanee program

The project is designed with the following objectives: Improving the statistical formulation for the recently developed stock assessment model for BC lakes so that it maybe fitted to more types of field data, e.g., stocking, gillnet test fishing and angling effort data, and applying it toimprove understanding of kokanee-rainbow trout interactions in lakes, assembling lake […]

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Découverte d’anticorps thérapeutiques humanisés ciblant TMPRSS2 neutralisant les virus respiratoires

Les infections respiratoires virales sont une problématique importante pour les systèmes de santé mondiaux. Plusieurs virus respiratoires tels que les coronavirus, responsables notamment de la COVID-19, et les virus de type influenza responsables de la grippe mutent rapidement ce qui leur permet d’échapper au système immunitaire et de résister aux traitements. Conséquemment, nous voulons bloquer […]

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Discovery of Novel Inhibitors to Mitigate Morphogen NODAL-mediated Proliferation of Cancer Cells using a Novel Genetically-encoded Bicyclic Peptide Ligand as Reference.

The proposed project will focus on discovering novel drug candidates as a targeted therapy for cancer using computational and synthetic approaches. 48Hour Discovery INC (48HD) aims to build a high-value drug discovery platform for internal drug discovery programs and for clients that provide synthetic molecules with drug-like properties to maximize the success of early drug […]

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MEMA_CB_CHEM : Metabolic Engineering of MicroAlgae for CannaBinoids – Chemistry PDF

The Canadian company Algae-C is developing innovative platforms for the growth of different kinds of phototrophic algae around the world. The algal biomass from its modular units is used for the aquaculture, biofuel, nutraceutical, chemical, and personal care markets. Algae-C wants to expand the use of their technology in more areas such as the pharmaceutical […]

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Using AI to Improve the Understanding and Diagnosis of Bipolar Neuroprogression

Traditionally, research into brain diseases has mainly focused on neurons. However, in recent decades, the brain’s blood vessels have taken a new spotlight. It is now known that when these blood vessels are damaged, potentially harmful substances can leak from the blood into the brain. In this project, I will study the role of leaky […]

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Characterization of ex vivo manipulated hematopoietic stem cells towards the improved production of safe and optimal blood grafts for therapeutical applications

Hematopoietic stem cells have the ability to sustain lifelong production of blood cells and are currently used to treat patients with various blood disorders via bone marrow transplantation. A critical aspect of using stem cells for therapies is their limited availability. Therefore, expansion and production of functional blood cells is essential to improve transplantation and […]

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Nutritional Prenatal Soft-gel Development

The requirement for dissolution testing (both routine sample and method development) is increasing for all of the current and future programs at Accucaps and is a regulatory requirement for most oral pharmaceutical products. The need for access to capacity and development capabilities for dissolution must reach beyond Accucaps. For these reasons, a collaboration with Dr […]

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An immersive VR-BCI-robotic interface for visuomotor rehabilitation augmentation.

Neurological conditions such as stroke are a major cause of disability in Canada, estimated to affect 1.5 million Canadians. Canadians living with neurological conditions face many ongoing challenges with reduced functioning and activity limitations. According to the World Health Organization, one in six people worldwide have a stroke. Two out of three survive, but up […]

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Examining the impact of an in-hospital intervention on veterinary team coordination, employee mental health and commitment, and veterinary hospital business metrics

Prior to the COVID-19 pandemic, there were mounting concerns related to the mental health and wellbeing of veterinary professionals, resulting in an increased rate of employee turnover across the profession. The COVID-19 pandemic has exacerbated these concerns, calling for veterinary organizations, such as VCA Canada, to emphasize business practices that promote positive client, patient, and […]

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Development of RNAi Enhancers using a yeast-based bio-manufacturing and delivery system and applications as a biopesticide against economically important crop pests in Canada

Biological pest control strategies (bio pesticides) offer promise as non-toxic and environmentally-friendly alternatives to conventional chemical pesticides. The use of RNA-interference as a potential biopesticide has become increasingly attractive due to its highly specific activity against target pest species, non-toxic and biodegradability, but as an emerging technology, has its limitations. This project aims to increase […]

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