Invasive fungal infections represent a major threat to human health that is exacerbated by the widespread emergence of antifungal drug resistance. Existing therapies are already limited in number, largely due to the similarity between fungal and human cells. As such, new antifungal approaches are urgently needed to combat drug-resistant fungal pathogens. We have previously implicated […]

Currently, mink producers select their breeding animals based on their phenotypic performances, and they have limited experience of using genetic or genomic selection to improve their profitability. Therefore, there is a need to enhance the ability of the Canadian mink industry to compete internationally by improving animal production using new genomic selection tools. Genomic selection […]

Globally, Canada has the highest prevalence of Multiple Sclerosis (MS). Diagnosis relies on magnetic resonance imaging (MRI) to monitor lesion development over time in the brain, spinal cord, and optic nerve. Despite its wide utility, MRI is not easily accessible. MRI requires a designated medical facility and expertise? is expensive, and needs to be done […]

Globally, Canada has the highest prevalence of Multiple Sclerosis (MS). Diagnosis relies on magnetic resonance imaging (MRI) to monitor lesion development over time in the brain, spinal cord, and optic nerve. Despite its wide utility, MRI is not easily accessible. MRI requires a designated medical facility and expertise? is expensive, and needs to be done […]

Asthma affects 1 in 8 Canadian children and is the leading cause of pediatric hospitalizations with costs to Canadian health care systems estimated to exceed 4.2Billion/year by 2030. While the causes are still debated, infant prematurity is a strong predictor for asthma. The altered gut bacterial community (microbiome) in preemies is suspected to contribute to […]

Asthma affects 1 in 8 Canadian children and is the leading cause of pediatric hospitalizations with costs to Canadian health care systems estimated to exceed 4.2Billion/year by 2030. While the causes are still debated, infant prematurity is a strong predictor for asthma. The altered gut bacterial community (microbiome) in preemies is suspected to contribute to […]

Aujourd’hui, le marché mondial du chanvre est en plein essor. En Belgique, la valorisation de cette plante multi-usage se fait majoritairement sur la graine, la fibre, et la chénovette. Cette plante est caractérisée par un métabolisme secondaire produisant des molécules à hautes valeurs ajoutées (comme le cannabidiol ou CBD et le delta-9-tetrahydrocannabinol THC). L’intérêt pour […]

Multidrug-resistant (MDR) bacterial pathogens are ubiquitous in hospitals and community settings. New antibiotics against unexploited targets are urgently needed to better control such infections. The proposed research aims to identify novel, drug targets and therapeutics for antibiotic-resistant nosocomial pathogens, capitalizing on a proprietary indel-targeting approach that takes advantage of structural differences between homologous essential human […]

We recently studied Western Canadian dairy farmers’ perspectives on outdoor access for dairy cows and identified 3 key areas requiring more research. Participants cited a lack of research on the effects of outdoor access for dry cows on transition cow health and farm profitability as a barrier to making an informed decision to provide outdoor […]

We recently studied Western Canadian dairy farmers’ perspectives on outdoor access for dairy cows and identified 3 key areas requiring more research. Participants cited a lack of research on the effects of outdoor access for dry cows on transition cow health and farm profitability as a barrier to making an informed decision to provide outdoor […]

Dairy calves are generally fed whole milk or milk replacer during the first weeks of life. Compared with whole milk, milk replacer containing vegetable oils has a higher polyunsaturated fat content. More specifically, it is high in omega-6 and low in omega-3 fatty acids, making the omega-6 to omega-3 fatty acid ratio ten times higher […]

We will investigate a new approach to improving the treatment of cancer patients. Chemotherapy and radiotherapy lose effectiveness and produce side-effects that are deleterious. For example, the development of scar tissue restricts the use of radiotherapy for several types of cancer. We will study a new type of drug, which will be supplied by our […]