With the imminent emergence of personalized medicine and the availability of costly targeted drugs comes the crucial allocation of ressources within the halthcare systems. Determining which treatment options should be funded has become an increasingly difficult task. Decision-makers are relying heavily on pharmacoeconomic (PE) evalutions to decide which of them will be most effective and […]

Development of a scalable, flow-through membrane-based processing platform for producing enriched fractions of bioactives from marine by-product extracts generated by bacterial fermentation. The proposed technology uses the conventional membrane filtration approach using pressure in tandem with applied voltage for increasing the value and application of the sustainably sourced, bioprocessed crude fish by-product protein extracts. Peptide […]

The purpose of the proposed research travel is to co-develop a working protocol for high-throughput chromatin conformation capture (Hi-C) sequencing using human post-mortem brain tissue at the single-nucleus level. I will be traveling to the lab of Schahram Akbarian (MD, PhD) at the Icahn School of Medicine at Mount Sinai in New York City. Dr. […]

Diabetes affects approximately 4 million Canadians. Diabetes is associated with increased risk of heart failure, which is also substantially more common after a heart attack. Patients with diabetes are particularly vulnerable due to the combination of these risk factors. As a result, risk models that can identify diabetes patients who are at the greatest risk […]

Our research focus is to understand the function of the PI3K family of enzymes, and the intracellular signals they produce, in immune system defenses and regulatory functions. Our specific aim is to understand how the dynamics of immune responses generated by B cells are controlled by these signaling enzymes to produce protective or ineffective immune […]

La mycotoxine désoxynivalénol (DON), chez le porc, entraine entre autre l’anorexie et l’affaiblissement de la réponse immunitaire. L’alimentation animale est mondialement contaminée par le DON. Le développement de stratégie antimycotoxine se bute au manque de compréhension de l’action du DON. L’hypothèse de la stimulation par le DON de l’axe neuroendocrinien Intestin-cerveau qui conduit à un […]

Attention is an important part of everyday functioning. We use it to interact with the world around us and take in new information. ‘AttentionTrip’ is a sophisticated tool that allows clinicians and researchers to measure the different components of attention, while it feels like you are playing a videogame. With this tool, we can see […]

Peu de connaissances existent sur la quantification des émissions de gaz à effet de serre (GES) et sur les pistes concrètes de réduction à l’échelle d’entreprises d’économie sociale oeuvrant en gestion des matières résiduelles. De telles démarches doivent être soutenues par une politique de développement durable pour implanter ces actions à long terme. Ce projet […]

La sténose de la valve aortique est la deuxième maladie cardio-vasculaire la plus fréquente et la maladie cardiaque valvulaire la plus fréquente. Sa prévalence au sein de la population ne cesse de croître. Non traitée, cette maladie est mortelle et seule une chirurgie permet d’empêcher sa progression. Il y a un besoin urgent de progrès […]

We want to determine the relationship between weather such as rainfall and temperature on outdoor grown hemp. Specifically what these variables do in terms of changing the content of THC and CBD in certain varieties of hemp. Our goal is to give farmers the knowledge so that they can determine when is optimal time to […]

Characterization of mode of action of C.minitans against S.sclerotiorum and documentation of lysis, hyhal-parasitism via electron microscopy. Studying its metabolite production during tripartite interaction of plant, pathogen and biocontrol agent through FTIR and NMR. Analysis on proteomic approaches during tripartite interaction by Fluorescent Two-Dimensional Difference Gel Electrophoresis (2D-DIGE), identification of protein and data analysis through […]

Winegrape phenology (the timing of seasonal events – leafout, flowering, harvest) has traditionally been an important tool for winegrowers to plan vineyard management. With warming, however, winegrape phenology has advanced significantly, impacting the type and quality of wine different vineyards can produce. How large the impact of climate change has been, and will be, depends […]