Recurrent neural network modeling of working memory

The temporary maintenance of information is known as working memory, and it enables behaviour that we take for granted, such as remembering a phone number or avoiding an obstacle after turning off the lights. Despite its importance for everyday behaviour, the neural mechanisms underlying working memory are/remain unclear. While some single-neuron recordings in monkeys correlate […]

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Chlorine dioxide as antibiofilm of surfaces in the extraction process of maple sap

This project proposes to expand the investigation of the use of chlorine dioxide (ClO2) as an antimicrobial agent in the sap extraction of maple syrup industry. It is well documented that chlorine dioxide exhibits antibacterial, antifungal, disinfectant, air sterilizer, antiviral, etc., properties. However, its mechanisms of action in specific applications, tolerable concentrations, toxicity etc., must […]

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Investigation of the Role of Host Proteins in the HIV-1 Envelope

While efficacious treatments are available for HIV, they require lifelong adherence and can have harmful effects over time. Therefore, developing novel treatments and a preventative vaccine remain critical. While most vaccine attempts to date have been largely unsuccessful, identifying new targets on the virus, may provide novel avenues for HIV vaccines and therapies. Integrin alpha […]

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Production of animal feed using Methylophilus methylotrophus

This project aims to identify an efficient fermentation strategy that will enable Cvictus to generate a protein-rich animal feed using methanol as the nutrient source. The key advantage of the production platform proposed by Cvictus is the use of a proprietary technology that can convert coal to methanol with ultra-low CO2 emissions. Initial research in […]

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Unraveling the electrophysiological basis of auditory entrainment from a gender perspective

An important challenge in developmental psychiatric research is to understand which are the neural mechanisms underlying language acquisition and speech comprehension. Auditory entrainment is the mechanism by which the brain faithfully entrains electrophysiological activity to rhythmically modulated stimuli, and it is seen as the mechanism that the listening brain use to attune to acoustic regularities […]

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Maximizing Plant Production using Light Emitting Diode Arrays

This proposal is for the development and optimization of light emitting diodes (LEDs) for plant growth. The development of LEDs over the complete range (and beyond) of photosynthetically active radiation (PAR: 400 – 700nm) now allows focused research into the effect of wavelength on specific plant responses. The LEDs produce light in a narrow spectrum […]

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Stability and antioxidant properties of pharmaceutical and nutraceutical products

Nutraceuticals are being used ubiquitously, but seldom undergo rigorous testing. This study is focused on two primary aspects of studying natural health products, specific cannabis and its oils. The first objective is to determine the shelf life (product stability) by performing a series of tests to accelerate the ageing process in order to provide an […]

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Probiotics to prevent the Progression of Non-alcoholic Steatohepatitis to Cirrhosis

As a result of increasing obesity, non-alcoholic fatty liver disease (NAFLD) is now the most common chronic liver disease. Non-alcoholic steatohepatitis (NASH) is the pathogenic form of NAFLD and can progress to cirrhosis and need for liver transplantation. There is currently no Health Canada-approved therapy for the treatment of NASH. The intestinal microbiome has been […]

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Examining Water Quality Parameter Testing Processes at Ontario Public Pools and Spas: Opportunities and Barriers

This research project aims to explore the experiences of public pool and spa staff in meeting the regulatory requirements for water parameter testing and understand user behaviours, needs, and attitudes towards pool and spa water testing equipment. Two groups of interest are Public Health Inspectors (PHIs) who are mandated to conduct inspections at public pools […]

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