Identification of blood-based biomarkers predictive of pulmonary exacerbations in cystic fibrosis

Individuals with cystic fibrosis experience recurrent episodes of worsen in respiratory symptoms, termed pulmonary exacerbations (PEx). Early identification of individuals who are at elevated risk of PEx can improve their clinical outcomes and rescue their lung function. In this project, we will collaborate with the Prevention of Organ Failure Centre of Excellence (PROOF) to develop […]

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Understanding the Mechanism of Probiotics for Human Health

DoseBiome has developed a new probiotic that targets several aspects of oral health: dental caries, periodontal diseases, and halitosis. This project aims to understand the exact mechanism of our probiotic’s inhibitory properties against the pathogens associated with the above diseases. DoseBiome is a new start-up in the probiotic/microbiome health sector, and this project will allow […]

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A cloud?based, multi?modal, cognitive ophthalmic imaging platform for enhanced clinical trial design and personalized medicine in blinding eye disease

Age Related Macular Degeneration is the leading cause of irreversible blindness in Canada and the industrialized world, yet there are no treatments for most patients. Tracery Ophthalmics has developed an imaging method, “AMD Imaging” (AMDI) that has generated unprecedented pictures of the retina (film of the eye) that include both known and unknown “flavours” of […]

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Development of new enzymatic products for optimization of paperproperties.

number of industrial processes, as well as on papermaking productivity. Such impacts have to be considered too in the emerging field of biorefining (production or extraction of high value products from forest biomass). The main partner to this project (Buckman Canada) has successfully introduced enzymes to the paper industry, but would like to expand its […]

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Diversity and Abundance of Beneficial and Pest Insects in Canadian Prairie Agroecosystems – Year two

The proposed research project will assess the insect fauna present associated with prairie wetlands, as well as those found in adjacent fields of crop plants (canola, barley, wheat) and restored grasslands. Insects will be collected using various trapping methods to sample taxa exhibiting different lifestyles. Collected specimens will be identified as specifically as possible to […]

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Intégration des technologies et thérapies associés aux soins de santé personnalisés (SSP)

Le secteur des soins de santé personnalisés (SSP) soulève de nombreux défis en matière d’adhésion, d’intégration et de réglementation. Il est alors nécessaire de faire l’état des défis et des enjeux concernant les SSP dans le système de santé. Lorsqu’on parle d’intégration ou d’adhésion des SSP, on fait référence à leur utilisation par les professionnels […]

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Evaluation of a radiomic approach based on hyperspectral retinal imaging to predict the cerebral amyloid status for the diagnosis of Alzheimer’s disease

The project will help Optina validate and further develope a novel technology to predict the presence of significant amyloid (A?) deposition in the brain from a simple, non-invasive hyperspectral retina scan in combination with an artificial intelligence algorithm. Accumulation of A? plaques in the brain is a key hallmark of Alzheimer’s disease (AD), but current […]

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Production d’acide succinique à partir de bio-méthanol en utilisantMethylobacterium extorquens comme mini usine cellulaire

L’acide succinique est l’une des 12 substances les plus importantes en chimie inudstrielle. Il sert, entre autres, à la fabrication de polymères tels le PBS (polybutylsuccinate). Présentement, 99% et plus de cet acide est fabriqué à partir de carbone non renouvelable (pétrole et/ou gaz naturel). Plusieurs compagnies et groupes de recherche travaillent activement au développement […]

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Root associated microbiome of trees growing in a fractured bedrock toluene phytoremediation site

Phytoremediation is a promising in-situ technology that uses plants and its associated microorganisms (particularly bacteria and fungi) to clean up contaminated soils. The efficacy of these processes however, requires an in-depth knowledge on the diversity of microbial communities closely interacting with plant roots. Several studies have demonstrated that plants growing in contaminated soils select for […]

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Root associated microbiome of trees growing in a fractured bedrock toluene phytoremediation site – Year two

Phytoremediation is a promising in-situ technology that uses plants and its associated microorganisms (particularly bacteria and fungi) to clean up contaminated soils. The efficacy of these processes however, requires an in-depth knowledge on the diversity of microbial communities closely interacting with plant roots. Several studies have demonstrated that plants growing in contaminated soils select for […]

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