Human papillomaviruses (HPVs) are responsible for almost all cervical cancers. Current treatment available relies on chemo- or radiation-therapy or surgery. These methods have several side-effects with high morbidity and survival of just ~ 70%. Our lab, therefore, develops a more patient-centered approach based on targeting the viral E6 protein, the main culprit of carcinogenesis in […]

Influenza is a viral pathogen responsible for annually claiming thousands of lives (~650 000 per year) and posing a significant threat to all human life. In Canada, Influenza pandemics lead to direct economic losses including medical costs (estimated mean cost per treatment: $14,612.00), and indirect losses such as substantial workplace absence (Avg 10.8 days). Additionally, […]

Phytoremediation (plant-based environmental cleanup) is a green, cost-effective alternative to conventional methods for contaminated site cleanup, which often involve extensive, community-disruptive, industrial efforts. Deep-rooted trees, such as hybrid Canadian poplars, can effectively be used to contain and clean up petroleum-derived contaminants in soil and groundwater resources. The proposed research project is aimed at verifying the […]

The purpose of this study is to explore the opportunities and challenges of alternative/renewable energy technologies in different regions, particularly Alberta and Bavaria (Germany), and their environmental impacts for proper policy decision making in relation to the interface of energy transition, climate change and environmental impact. The project is significant because it will contribute to […]

Scleroderma or Systemic Sclerosis (SSc) is an autoimmune disease characterized by progressive fibrosis of skin and multiple internal organs and prominent and often severe alterations in the microvasculature. Although SSc is the third most common systemic inflammatory autoimmune disease, there is currently no effective disease-modifying therapy for SSc. The overall objective of this project is […]

While studies show that dietary fibres are beneficial in many diseases, they are not digested or absorbed directly by the host, but rather fermented by gut microbes. Fermentation byproducts (mostly short-chain fatty-acids; SCFAs) are responsible for health benefits. Only select inflammatory bowel diseases (IBD) patients benefit from fibres; many patients report sensitivity to high fibre […]

While studies show that dietary fibres are beneficial in many diseases, they are not digested or absorbed directly by the host, but rather fermented by gut microbes. Fermentation byproducts (mostly short-chain fatty-acids; SCFAs) are responsible for health benefits. Only select inflammatory bowel diseases (IBD) patients benefit from fibres; many patients report sensitivity to high fibre […]

There are gaps in our knowledge concerning calf nutrition when producers feed high amounts of milk to calves along with starter feeds differing in nutrient composition. Mainly, how these calf diets alter lower gut development and health during the pre- and post-weaning periods. This research will utilize pre-weaning calves to assess the effects of diets […]

Older adults are the largest growing segment of the Canadian population. Almost 40% of men and 59% of women aged 65 to 79 years experience sleep disturbances. Non-pharmacological interventions, such as educational programs and exercise, can improve quality of life of older individuals by enhancing sleep quality. Although strong evidence suggests that virtual reality (VR) […]

A diversity of native bee species inhabit agricultural and urban landscapes and can be more effective pollinators than the widely employed European honey bee. However, honey and wild bee communities often overlap, which means these bees compete for the same floral resources. Studies of competition between wild and managed pollinators are limited due to methodological […]

A diversity of native bee species inhabit agricultural and urban landscapes and can be more effective pollinators than the widely employed European honey bee. However, honey and wild bee communities often overlap, which means these bees compete for the same floral resources. Studies of competition between wild and managed pollinators are limited due to methodological […]

In the last years imaging using miniature microscopes (mini-microscopes also called mini-endoscopes) has become a method of choice for the understanding of activity at the cellular and network levels in different brain regions, in freely behaving animals. However, mini-microscopes are connected with wires to other devices, which largely alleviate the use of these imaging systems […]