The Sorensen laboratory-based Childhood Cancer Research Program is specifically focused on elucidating the genetic and biological determinants of the metastatic process in childhood cancer. Metastatic disease remains the single most dominant driver of adverse outcome in most childhood cancers, particularly in childhood sarcomas. Research in the program is dedicated to uncovering the mysteries of metastatic […]

Schizophrenia is a devastating disease for which there is no cure. Available treatments aim at minimizing the symptoms. However, patients often stop taking their tablets, which leads to a worsening of their symptoms, referred to as relapse. In order to avoid the problems of discontinuation, some treatments are administered through an injection. Several studies have […]

Opioid-related harms such as abuse, misuse, addiction, diversion and overdose have been rising exponentially, a phenomenon referred to as the opioid epidemic. The current research will examine federal and provincial risk minimization measures (RMMs) regarding the opioid epidemic starting in 2016. We will develop a landscape of federal and provincial opioid RMMs, describe trends over […]

Parallex BioAssays est une jeune biotech issue de travaux de recherche universitaire en génie biomédical. Au cours des dernières années, ils ont développé la SnapChipMC… un nouvel outil de laboratoire qui permettra d’accélérer la recherche biomédicale en mesurant plusieurs protéines à la fois, sans aucun compromis sur la qualité des résultats. Au cours de ce […]

For some diseases, several treatments are available and it is therefore necessary to compare their effectiveness. When several studies have been published on such comparison, it is becoming common practice to combine the results through a method called meta-analysis. Combining results is however challenging owing to differences in populations and methodologies between studies. Not to […]

Les milieux humides jouent des rôles très importants dans notre environnement par le biais de multiples services écosystémiques qu’ils offrent. Par exemple dans un bassin versant, ils servent de réservoirs tampons contre les inondations en aval; ils purifient l’eau de la nappe phréatique et des ruisseaux en servant de lieux de dépôt et d’extraction des […]

Many people in Canada are aging and/or may be living with a disability. These people often have to rely on caregivers, and are limited in what they can do independently. Novalte has developed a SMART technology system that connects to WiFi devices in the home to allow someone living with a disability more independence and […]

Ce projet consiste à recenser les effets secondaires et à caractériser le profil d’innocuité d’une nouvelle formulation d’un médicament bien connu et efficace dans le traitement de l’addiction aux opioïdes : SublocadeTM (buprénorphine à libération prolongée). Tout en agissant sur l’humeur, les opioïdes génèrent un sentiment d’euphorie et c’est pourquoi ils peuvent comporter un risque […]

Le monde de l’économie de la santé est en constante évolution entre autres en raison des nouvelles sortes de traitements et de l’importance, qui peut s’avérer parfois urgente, de l’accès aux médicaments. Ainsi les agences d’évaluation des technologies de la santé essayent de s’adapter au mieux à ces changements. En juillet 2018, l’INESSS a apporté […]

Echinoccocus multilocularis (Em) is a deathly parasite that can affect humans and is considered as a global emergent pathogen. Recent findings indicate that the parasite is expanding its geographic range in North America and that the highly pathogenic European strain is the most prevalent in Western Canada (Alberta, British Columbia, and Saskatchewan). Therefore, I will […]

Recent studies have demonstrated the efficacy of medical cannabis (MC) to treat certain conditions like chronic pain. However, surveys conducted before 2018 have revealed that physicians were more reluctant than patients to use MC. According to physicians, a major barrier to the use of MC was insufficient information. In this project, we want to describe […]

There are several drugs on the market whose overall safety may not be fully known. Drug safety monitoring is important in identifying previously unknown side effects. This activity is not exclusive to drugs, but also applies to natural health products. Patient awareness of product safety is a major concern in Canada. Only about 5% of […]