National Legalization of Cannabis has occurred in Canada. Very little is known about the different compounds in the Cannabis Plant. The two main compounds are THC and CBD. Both of them have shown some benefits for different conditions. We would like to determine the best dose and ratio of compounds within the Cannabis plant for […]

Chronic neuropathic pain affects millions of Canadians for which the government spends ~$6 billion a year on treatment. It is therefore imperative to find new therapies with few side effects and high therapeutic efficacy. This study will examine the therapeutic properties of cannabidiol (CBD), which is a non-intoxicating component of cannabis. Studies have shown that […]

Osteoarthritis is a progressive joint disease that causes pain and stiffness, resulting in a decrease in quality of life for patients. Treatment include intra-articular administration of crystalline corticosteroids or hyaluronate. Intra-articular corticosteroids, due to the large doses required, short residence time in the joint, and crystalline structure, are associated with cartilage damage and a short […]

We all know someone affected by breast cancer. Many of us have also heard that we can reduce our risk of experiencing breast cancer from what we eat. Much of this comes from studies that compare people who got sick with those who didn’t and trying to understand what makes them different. But what is […]

We will use a database of more than 30 years of scientific survey and citizen-science observations of common loon breeding on lakes in Ontario, as well as other parts of Canada, to determine whether loons now breed successfully on lakes where they were negatively affected by acid rain (and other human threats like development). Our […]

Since the Brainnetome Initiative and Human Brain Project began, a few efforts have been made to address the computational challenges of neuroscience Big Data. The promises of these two projects were to model the complex interaction of brain and behavior and to understand and diagnose brain diseases by collecting and analyzing large quantities of data. […]

The main aim of the project is to find new mechanisms by which Inducible nitric oxide synthase (iNOS) expression is regulated in human cells. Regulation of iNOS through post-translational mechanism stage can give better results. That is why in this project iNOS expression is controlled at the post-translational level. High concentration of NO can cause […]

Neurodegenerative diseases have caused massive economic burden on the healthcare system as well as reduced patient and caregiver’s quality of life. Identifying biomarkers for early clinical diagnosis, tracking of disease progression, and evaluation of treatment therapies is critical. However, developing such tools remains a significant challenge. The goal of this project is to manage and […]

La transformation du concombre de mer (Cucumaria frondosa) est une activité récente au Canada, présente au Québec et au Nouveau-Brunswick. Cette nouvelle pêcherie a su trouver des marchés lucratifs en Asie et joue maintenant un rôle crucial pour maintenir l’activité économique de communautés côtières dévitalisées. Actuellement, la transformation du concombre génère beaucoup de coproduits (40% […]

Beer production is only as good as the yeast that make it. When yeast are first pitched for brewing, they produce the desired fermentation product—beer. But, after numerous cycles of fermentation, the yeast become exhausted and produce beer with unwanted flavors and alcohol content. As such, the beer is no longer fit for consumption. Over […]

En réponse au phénomène de la résistance aux antibiotiques, il y a beaucoup de pression pour diminuer voir cesser l’utilisation des antibiotiques dans les élevages. Plusieurs alternatives aux antibiotiques ont déjà été commercialisées et d’autres sont en développement. Selon des expériences précédentes dans notre laboratoire, les produits naturels offriraient une solution intéressante pour contrôler Clostridium […]

Personalized health is increasingly gaining public attention in the media as the future of healthcare. Personalized health is the idea that medical treatment will be tailored to the individual based on their predicted response or risks of disease. Omics analysis, defined as the universal detection of different classes of biological molecules, has the potential to […]