The Centre for the Commercialization of Antibodies and Biologics (CCAB) is working with Empirica Therapeutics (Empirica), a Canadian start-up company focused on developing data-driven treatments for cancer, to address the unmet medical needs of glioblastoma (GBM), the most common adult malignant primary brain tumor. Current therapies are only partly effective, with frequent relapse and poor […]

Au Québec, les fermes marines ayant un intérêt pour l’algoculture sont situées aux Îles-de-la-Madeleine, en Basse-Côte-Nord et en Gaspésie, sur des sites dont les caractéristiques sont très différentes. À cet effet, une entreprise maricole de la Gaspésie, Ferme Marine du Québec, produit commercialement des plantules sur cordes et vend des collecteurs d’algues à des aquaculteurs […]

Chronic Obstructive Pulmonary Diseases (COPD) is a lung disease that cause a lot of suffering to the Canadian population. To accelerate the drug discovery process, an old blood pressure lowering medication was tested to block the progression of COPD. A patient study showed that the old medication did provide some protective effect to the lung […]

Algae-C is a company specialized in algal biomass production. It enables on-site production of algae for a wide variety of sectors (aquaculture, nutraceutical, cosmetic and biofuel). To date, many fuels, pharmaceuticals and cosmetic products are extracted from plants. These valuable plant natural products (PNPs) are often produced in low quantities in plants and extraction methods […]

Pour délivrer des médicaments, les formulations solides à administration orale sont préférées par les patients et l’industrie pharmaceutique. De plus, les excipients sont préférablement des polymères biocompatibles d’origine naturelle. Les propriétés spécifiques des excipients (solubilité, susceptibilité aux enzymes gastro-intestinales) peuvent rendre difficile l’utilisation d’un seul polymère pour la livraison de l’actif à chaque segment du […]

Clearcut logging and acid deposition affect plants, lichens and slugs (lichen consumers) and may facilitate the introduction and spread of alien invasive slugs, which can increase grazing pressures on at-risk lichens. The main research goal of this project is to improve our understanding of how clearcutting practices affect herbs and slugs and facilitate both the […]

Le projet vise la préparation d’un protocole de contrôle de qualité pour l’insecte parasitoïde Trichogramma ostriniae. Cet insecte est utilisé comme agent de lutte biologique contre la pyrale du maïs dans les cultures de maïs sucré frais. L’entreprise Anatis Bioprotection inc. produit ce parasitoïde et doit donc se pourvoir d’un tel protocole. Dans un premier […]

The objective of my research in the Fillingham Lab at Ryerson University is to understand how genes works since it is a fundamental process and its failure is implicated in many diseases. Understanding how genes works has shown to have promising outcomes in the treatment of many diseases since this research can reveal novel drug […]

Combating infectious disease pathogens is a pressing global health challenge. Due to limited treatment options, fungal pathogens pose a unique challenge, and are emerging as a leading cause of human mortality. Focusing on Candida albicans, the most common cause of fungal infections, our research project aims to understand how different genetic factors play a role […]

Natural communities are undergoing accelerated changes due to human pressures such as habitat fragmentation and species invasions. One way of anticipating community responses to these changes is through dynamical food web models whereby key species traits are altered and the community repercussions are assessed. These modeling approaches, however, overlook the spatial dynamics which are critical […]

Enzymes are important biological catalysts which span all domains of life. They play vital roles in the metabolism and production of biomolecules in different organs. Our interest lies in using enzymes to develop biosensors to be employed in studying neurochemical processes occurring in the brain. The purpose of this project is express and characterize three […]

Several classes of psychotropic compounds have been increasingly shown to possess antimicrobial properties with possible implication in microbiota-gut-brain axis. For instance, sertraline and paroxetine are efflux inhibitors in bacteria cell walls and are effective on gram-positive bacteria such as Enterococcus and Staphylococcus. Therefore, a comprehensive assessment of the antimicrobial effect of these chemicals on gut […]