Les bryophytes comme bioindicateurs des changements climatiques

L’industrie forestière est un pilier de l’économie Canadienne. Sa compétitivité dépend des certifications environnementales et donc de sa capacité à démontrer la compatibilité de ses pratiques avec le maintien de la fonctionnalité et biodiversité de l’écosystème. Seulement, dans le contexte actuel des changements climatiques, cette équation se complexifie. Les modifications des conditions de température et […]

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Development and production of [18F]-DCFPyL, a PSMA-based radiotracer to support recurring prostate cancer PET clinical studies

This project that aims to develop and establish the production and analyses of a radioactive product at the CRCHUM Radiochemistry and Cyclotron laboratory for future use in human clinical trials using an imaging methodology called positron emission tomography (PET). This PET probe allows for the detection and measurement of Prostate-Specific Membrane Antigen (PSMA), a protein […]

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Genetic monitoring of a sockeye salmon repatriation to improve interactive fisheries management

Re-establishing salmonid populations to areas historically occupied has substantial potential for conservation gains, however, such interventions also risk negatively impacting native resident stocks. An on-going reintroduction of anadromous sockeye salmon (Oncorhynchus nerka) to Skaha Lake, British Columbia is succeeding, with large numbers returning to spawn. However, a recent genetic study detected strong evidence of hybridization […]

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Crif1 : Protein expression, purification and crystallisation

Human Crif1 is a protein with multiple functions, playing important roles in embryonic development, cellular stress, cell cycle regulation and mitochondrial membrane integrity. CRIF1 is coined to play a regulatory role in the Bone Marrow microenvironment-induced leukemia cell cycle arrest possibly through interacting with CDK2 and acting as a cyclin-dependent kinase inhibitor. In this project, […]

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Looking at the Physical and Psychosocial Outcomes of an After-School Physical Activity Intervention for Children with Congenital Heart Disease

The research intern will be working with Sportball to offer one of their multi-sport after-school programs to children who are living with serious heart defects. Physical activity has many health benefits for children, and after-school programs are an effective way to increase daily physical activity levels. Children living with heart disease are a vulnerable group […]

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An analysis of Delivra LivSport PreWorkout Cream combined with oral creatine to improve muscular performance and alter arterial stiffness

Creatine is a supplement known to improve performance over repeated high intensity exercise, seen in most sports. Typical creatine supplementation involves ingesting large amounts of the supplement, leading to side effects of weight gain and GI distress. Delivra™has formulated a new way to supplement creatine through a topical cream applied to the legs, which can […]

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Evaluating the prospective benefits of physical demands description (PDD) data created from job simulations

Every job at Ford Motor Company should have an associated document describing the physical demands (i.e., lifting, climbing, pushing, etc.) required in that job. This information is important to select job candidates with the right blend of capabilities to be able to safely meet these demands. Perhaps more importantly, this information also provides a benchmark […]

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Utilisation de bois raméal fragmenté pour faciliter la recolonisation forestière sur roches stériles d’une mine d’or

Pour rétablir l’écosystème forestier sur roches stériles minières, la recolonisation naturelle à partir de la forêt environnante présente plusieurs avantages. Mais l’établissement des essences forestières requiert des conditions qui font défaut aux roches stériles. Du fait de leur manque en matière organique, ces substrats dégradés manquent de nutriments, d’eau, et d’organismes du sol. L’utilisation d’un […]

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Mevalonate Cascade Inhibition Sensitizes human Glioblastoma Cells to Temozolomide via Modulation of Autophagy

Glioblastoma multiforme (GBM), also known as glioblastoma and grade IV astrocytoma, is the most common and most aggressive cancer that begins within the brain. There is no clear way to prevent the disease. Typically treatment involves surgery after which chemotherapy and radiation therapy is used. The medication Temozolomide (TMZ) is frequently used as part of […]

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Préparation de la SnapChipMC en vue du développement d’un essai multiparamétrique pour l’étude du diabète

Pouvoir mesurer la concentration de différentes protéines est important pour l’avancement des connaissances médicales. C’est malheureusement un travail qui demande souvent beaucoup de temps. Parallex BioAssays est une jeune entreprise montréalaise développant présentement un outil qui permettra de mesurer simultanément la concentration de plus de 100 protéines, sans compromettre l’exactitude des résultats. L’objectif visé au […]

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Fish bioacoustics: characterization of fish sounds and effect of noise on fish

Fish produce sounds underwater to communicate with each other. Underwater microphones (called hydrophones) can be deployed in the ocean to record these sounds and help scientists study where the fish are without disturbing them. Unfortunately, few studies have been done on fish sounds and a lot of sounds fish produce have not been identified yet. […]

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