Genetic susceptibility to renal cancer

Renal cell carcinoma (RCC), the most common type of kidney cancer, is characterized by heterogeneous tumor biology and clinical outcomes. Due to the indeterminate behavior of RCC and the absence of routine biomarkers, it is difficult to identify individuals at risk to develop RCC, and patients who are at high-risk of relapse. There are also […]

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Promoting Water Stewardship Through Citizen Science with Water Rangers

Water Rangers uses citizen science to acquire baseline data for water bodies across Canada by giving and selling testkits to volunteers across Canada. This project will explore who is most likely to take part in water testing, what engagement strategies reduce dropout rates, and how testing water increase environmental concern by changing values and people’s […]

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Optimization of Bioink Composition for Efficient Mesenchymal Stromal Cell Chondrogenic Differentiation in an Animal Component-Free Culture

Culture of cells in three-dimension (30) allows cells to interact with their surrounding and grow in all directions and behave in a manner that is more closely associated to how they would in vivo as long as their nutrient and environmental requirements are maintained. In this context, bioprinting offers an advantage over 20 cell cultures […]

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Development of cold anesthetization and packaging technologies for waterless transportation of live shrimp

Warmwater shrimp are dominant in Canada’s shrimp market, and they are mainly imported from Asian countries. Final market value of the imported shrimp can be increased if they are alive; however, shipping live shrimp in water is cost-prohibitive. To reduce the weight-associated cost, shrimp growers are interested in transporting live shrimp in waterless conditions. Unfortunately, […]

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Investigation of Low-Ductility Geogrid Reinforcement for Ground-supported Concrete Structures

Steel rebars are the dominant reinforcement elements in reinforced concrete structures due to their relatively adequate manufacturing, material property and established construction codes. In an ideal environment and under nominal loading, conventional concrete reinforcement is expected to govern the design strength based on which they are designed. However, under environmental loading conditions, such as very […]

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Networks and Smart Sensors for Safety-Critical Avionics Applications

High channel count sensor and actuator devices are needed to tackle a growing number of functions in aircrafts. With traditional avionics technology, connecting these devices results in bulky wiring bundles. The stringent safety standard of avionic systems requires redundant installation of all components on board, which further exacerbates the situation. Moreover, in new avionic systems, […]

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Exploration of Novel Fuels for Gas Turbine Applications

The internship for each student will be under the supervision of Gilles Bourque PhD, the Combustion Research and Technology Team Leader. Mr Bourque has been working for the past 12 years at RR Canada of which 10 in the Combustion department. The student will be an integral part of his team and as such will […]

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Erosion studies of southern Ontario tills and St. Lawrence Valley marine clays and assessment of an extreme precipitation prediction approach

Quaternary glacial deposition has covered much of southern Ontario with tills and the Saint Lawrence Valley with marine fines. Rivers incised into these materials exhibit particular geomorphologic behavior. Civil engineering works built either in (e.g. dams, bridge piers, etc.), beside (linear infrastructure such as roads, railways, etc.) or across (e.g. bridges, etc.) such rivers must […]

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Optimization of rice and other protein based extrusion encapsulation

The proposed project deals with the extrusion encapsulation of bioactive components using rice and corn protein based food matrix. It is well recognized that the performance properties of natural lake pigment encapsulated products are influenced by the structural properties of the matrix protein used for the extrusion encapsulation. The type, mixture and nature of proteins […]

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Visualization of manufacturing complexity highlights on CAD file

Currently, the service provided by GRAD4 allows online storing and sharing of computer-aided design (CAD) models. However, there is no interface developed for visualization of CAD models in the service in a fast and comprehensible way to the users: both manufacturers and buyers. The main challenge of such implementations is in relatively high computational cost […]

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New therapeutics against T-cell acute lymphoblastic leukemia

A protein named c-Myc is causally implicated in over 50% of all human cancers. Preliminary work supports two proteins (POZ domain protein and c-Myc cofactor Miz-1) as a new drug target to disable c-Myc function. We have identified small molecules which act on this target and will now serve develop a series of optimized and […]

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Development of an Aerosol Retrieval Algorithm for the GHGSat high resolutionGreenhouse Gas Monitoring Satellite

GHGSat has built the first and only satellite that makes measurements of greenhouse gas (GHG) concentrations at high . spatial resolution (< 50 m). Currently, the GHGSat data processing algorithm only retrieves GHG information from our atmospheric measurement data. However, the atmosphere also contains aerosols that complicate the accurate retrieval GHG concentrations. Developing an appropriate […]

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