More than half of all women suffer from some form of pelvic floor disorder over their lifetime, with pelvic organ prolapse and urinary incontinence being the two most common presentations. High impact physical activity is one risk factor for the development of pelvic floor disorders, where it has been postulated that repeated impacts experienced chronically […]

The current production methods for new generation refrigerants (HFO-1234yf) used in cars, refrigerators, air-conditioners, etc. require energy intensive and sometimes corrosive conditions. The current project seeks to reduce or eliminate these two caveats. We propose, by using readily available feedstock or by-products from Teflon manufacturing, we could use our process to easily manufacture HFO-1234yf. Using […]

Echinacea purpurea is a popular herbal medicine with a global market of ?$1 billion but there is tremendous variability yet limited distinction between the products on the market. Amway Canada is a leader in the production and distribution of Echinacea products, and now aims to leverage the company`s unique Echinacea resources by sequencing the plant`s […]

There are currently no practical-economical repair methods for many aerospace parts made of aluminum/titanium. The Cold Spray technology produces metal coatings by accelerating metal powders onto the substrate to be coated using high velocity jet at supersonic speeds. Upon impact the particles plastically deform and produce a dense coating. Metals such as aluminum/titanium can be […]

Efficient pumping function of heart depends on receiving oxygen and nutrients through heart’s specific blood vessels called coronaries. In case of coronary stenosis (e.g. plaques formation on their inner walls), the heart muscle cannot function normally and may be permanently damaged. Three treatment strategies are broadly available that include medications, coronary stent placement and coronary […]

Efficient pumping function of heart depends on receiving oxygen and nutrients through heart’s specific blood vessels called coronaries. In case of coronary stenosis (e.g. plaques formation on their inner walls), the heart muscle cannot function normally and may be permanently damaged. Three treatment strategies are broadly available that include medications, coronary stent placement and coronary […]

This project will be focused on implementation of an algorithmic model to help us better understand the underlying processes of recognition memory. Specifically, our computational model is comprised of two memory modules – one representing the hippocampus and the other representing the perirhinal cortex of the brain. According to the dual-process model of recognition memory, […]

Desiccation-induced cracking is a complicated phenomenon associated with strongly coupled hydro-mechanical behavior of cohesive soils. The soil-shrinkage characteristic curve (SSCC) for intact soils is well established to describe the relationship between void ratio and water content. However, it is questionable to employ the SSCC to predict the volume change based on the reduction in water […]

Osteoarthritis is an extremely common, extremely costly disease that will become more prevalent as the population ages. Treatment delivered in primary care settings does not always reflect ‘best practice’ care for the disease. In particular, non-surgical and non-drug interventions such as exercise, weight loss and education regarding self management are underutilized. One reason that clinicians […]

The Élisabeth Bruyère Research Institute is interested in addressing an organizational challenge associated with its size and the geographical location of its partners, which form a research community that is spread over multiple sites located in distant parts of the city. The large number of researchers and physical disconnection of the buildings limit social interaction […]

Regulations are introduced to ensure the well-being, safety, and other societal needs of citizens and organizations. Yet, regulators often have difficulties assessing the performance of their regulations, and whether regulatory initiatives actually improve compliance. This project’s main objective is to investigate the suitability of a framework combining a standardized goal modeling notation with an existing […]

The intern will be producing a therapeutic protein, i.e. ‘biologic’ (BMP2) using mutated bacterial plasmids as the bio-factory. The intern will create a sequence of DNA to be transformed into E. coli cells (BL21). The cells will be grown up in the lab, and studied for enhanced clinical efficacy. Proteins will be affinity purified and […]