Advances in Whole Slide Imaging (WSI) and Machine Learning (ML) open new opportunities to create innovative solutions in healthcare and in particular digital pathology to increase efficiencies, reduce cost and most importantly improve patient care. This project envisions the creation of new automated ML tools including the design of a custom Convolution Neural Network (CNN) […]

Mobility in the home is a difficult task for older adults with mobility limitations and is associated with a risk of injury from falling. However, it is a requisite for maintaining independence. A number of assistive technologies have been developed to help a number of different activities of daily living, one in specific is the […]

Treatments generating ablation and coagulation of tissues by applying lasers, microwaves, radiofrequency currents or focused ultrasound have many advantages over scalpel-based and other mechanistic surgical methods. These advantages have consequently motivated the clinical application of the various ablation techniques in a myriad of medical specialities, such as oncology, electrophysiology, and ophthalmology. Despite these advances, most […]

Enacting complex behaviours, such as locomotion, involves network-wide integration of information at the level of the nervous system. This understanding highlights the need for appropriate technologies to monitor the global dynamics of neurons in these networks. However, previous studies employing model organisms have been limited to low resolution imaging, few neurons and/or immobilized specimens. In […]

A novel class of DHODH inhibitors called tetrahydroindazoles was recently identified in the group of professor Sonia Lain through screening of a commercially available chemical library for activators of p53. The hit compound HZ00 is able to slow tumor cell growth in culture, an effect which was reversed upon supplementation with uridine, and had little […]

Oxidative stress and inflammation can cause neuron degeneration and lead to mental disorders such as Alzheimer’s Disease. Dementia is debilitating and poses economic burden to the patients, families, and society. Currently, no curative drugs have been developed to treat dementia. This study will be elucidating the mechanism of action and examining the anti-oxidative and therapeutic […]

Color has been a central issue in the digital imaging device industry. Customers want more vivid and natural color presented on imaging devices such as displays, printers, and cameras. Among various colors in the display system, skin color is the most critical references since it has the most perceptive impact on human visual system and […]

Coronary artery disease (CAD) occurs when buildup of plaque causes blockage of oxygen to reach the heart. When a total blockage occurs, this leads to heart attacks. CAD is the leading cause of death worldwide and this research will be conducted on a mutation found in a gene associated with plaque build up and analysis […]

Chlorinated organics are recalcitrant in nature and are released from industrial effluents. Advanced oxidation processes (AOPs) such as photo-catalysis are considered effective towards partial or complete degradation of toxic and recalcitrant compounds due to their non-selective nature. The current study is planned to synthesise bimetallic catalyst supported on carbonaceous waste material. The catalyst synthesized will […]

The proposed research will take place in Mt. Abu, Sirohi district of Rajasthan in Western India. Mt Abu is a batholith and consists of granite. The project will analyze the 735 Ma old Mt. Abu Granitoid batholithic pluton that is situated at the southern tip of NE trending in the Aravalli Mountain Range. The purpose […]

Chronic tinnitus, a constant ringing in the ear, is a major cause of disability in modern society. In particular, hearing loss-induced tinnitus is often present with various comorbidities including insomnia, deficits in attention, anxiety and depression which severely affect the quality of life. Unfortunately, there are limited therapeutic treatments to alleviate tinnitus. Currently, it is […]