Antibodies are used for treatment of many diseases, including cancer. Within the human immune system, antibodies fight invading bacteria and viruses. We have devised a way to make high-quality antibodies in the laboratory and target them to specific disease-related proteins that have been identified by the scientific community and in our lab. Ensuring that these […]

Groundwater contamination by hydrocarbon fuels such as gasoline and diesel fuel is a serious threat to the environment and human health. Sources of this contamination include leaking underground storage tanks, pipleline breaks, tanker truck accidents and train derailments. There is a need for improved understanding of the mobility of hydrocarbon fuels in the subsurface to […]

Engaging with visual displays is not always feasible or desired. They could be absent in certain contexts due to their fragility, cost or high battery consumption. Visual attention could be engaged elsewhere in an activity or be impaired due to disabilities. With the rise of wearables that remain in constant, sturdy contact with the skin, […]

The NSERC Strategic Network for Smart Applications on Virtual Infrastructures is a five-year partnership between Canadian industry, universities, researchers, research and education (R&E) networks, and high performance computing centres to investigate the design of future application platforms that will deliver software applications of greater capability and intelligence. These application platforms will be supported by an […]

Rupture of cerebral aneurysms often leads to mortality or sever morbidity in most cases. Pathogenesis of aneurysms has been attributed to abnormal flow-induced forces that act on the vessel walls. These forces are typically measured by first recreating patient’s aneurysm model from medical images, and, afterwards, using these as input for computational fluid dynamics (CFD) […]

The central goal of this research project is to broaden measurement of school performance across Canada by developing, collecting, and measuring data on six performance indicators as follows: academic achievement, physical health, social-emotional development, creativity, citizenship, and school climate. Having developed competencies in these areas during phase one of the project, the current phase aims […]

Hundreds of thousands of endemically poor children are in need of quality prostheses. Current manual processes of prosthetic production are labour-intensive and slow. Moreover, the World Health Organization (WHO) estimates a shortfall of 40,000 trained prosthetic technicians in low/middle income countries. Without the enhanced mobility provided by prosthetics, these children suffer from a dramatically reduced […]

Absence seizures are the most common form of epilepsy in children. These patients often experience transient episodes of impaired consciousness, which have an enormous impact on their quality of life. We are proposing to identify the neural substrates for these seizures. These experiments would provide the basis of future experimental studies examining the biological basis […]

This research project is responsible for the design, development, and experimentation of the actuation and control systems for synchronized segmentally interchanging pulley transmission system, SSIPTS. SSIPTS is a novel variable mechanical transmission that offers the combined benefits of existing transmission systems for both automotive and wind industries. To ensure high reliability at the high speed […]

This project explores the relation between internationalism and leftist literature in early twentieth century China and East Asia. A study of internationalism amongst leftist movements offers important insights into technologies and strategies for building coalitions across national, linguistic and cultural boundaries. I propose that examining workers organizations and their literary and cultural links to internationalism […]

Significant advances in technologies related to antibody discovery and development have allowed therapeutic antibodies to become the fastest growing class of biopharmaceuticals over the last 20 years. Northern Biologics is a biotechnology company that seeks to develop therapeutic antibodies for the treatment of cancer and fibrosis. Together with Dr. Jean-Philippe Julien at SickKids (University of […]

In some parts of the world, airport runways are not constructed and maintained to the standards expected in North America and Western Europe. Aircraft designed for use on smooth runways may not be certifiable when they are operated on rougher runways because the predicted load cases associated with landing and take-off are very different from […]