Due to the unpredictable location of coronary artery bypass grafts (CABG), angiography for CABG patients costs catheterization labs additional time, poses an added risk to patients, and incurs extra costs, therefore using additional resources at Sunnybrook Hospital and at a national scale. The development of an assistive software product that helps cardiologists find free graft […]

After severe skin injury such as burns, our body rapidly but imperfectly repairs the damage, leaving behind a stiff scar. Scarring is a clinical burden because skin is losing vital functions. If scars form in internal organs, e.g., in the heart after myocardial infarct, the outcome can be lethal. During normal tissue repair, local fibroblasts […]

Engineering consulting is a unique occupation that requires professionals to possess both strong technical and non-technical abilities. Engineering consulting organizations have identified the the gap between top performers and their peers to pertain to be social, relational and leadership skills. Our work seeks to identify the leadership skillset that differentiates top performers in engineering consulting […]

Skeletal muscle, an essential organ system making up 30-40% of total body mass, is unique in that it allows for the body’s voluntary movement. It is solicited and stressed daily and consequently possesses the remarkable ability to regenerate in response to injury due to a special population of cells named muscle stem cells (MuSCS). At […]

The ability to simulate chemistry accurately allows for significant developments in many fields such as material and drug discovery. Unfortunately, the underlying equations that describe chemistry become exponentially harder to solve as we increase the size of the system. This makes it impossible for us to accurately simulate useful molecules on classical computers. A potential […]

Our goal is to employ a host of new compounds, made by the applicant in her lab in Brazil, for drug discovery studies at the University of Toronto. Specifically, the host uses a technique called Nuclear Magnetic Resonance (NMR) to obtain signatures of drugs or ligands. These signatures can identify those compounds which bind strongly […]

The aim of this project is to assess the long-term impacts of transport poverty in Canada using mixed methods approach. Transport poverty is the combined effect of transport disadvantage (including but not limited to inadequate public transport options, poor public transport accessibility, not owning or having access to car, perception of safety) and various socio- […]

Asbestos was once used extensively in the fabrication of a variety of products and materials. After being declared a carcinogen and linked with a variety of lung diseases more than 2 decades ago, the use of asbestos was banned in many countries. Yet, asbestos remains a public health concern worldwide and one of the leading […]

Amber is a novel preservation media for diagnostic tissue biopsies that enables superior histology, biomarker viability, and high RNA quantity. Amber is proposed to increase visualization of tumor margins on MRI. The current challenge of evaluating post-surgical specimen is the MRI technology is succumbed to surgically induced artefacts from tissue-air interface. Tumor margin detection is […]

The field of responsible investing is rapidly expanding, with even greater attention on the importance of responsible investment with each passing year, as seen most recently in the aftermath of the impactful 2021 COP26 summit, where responsible investment was key focal point. Directing our financial resources in a sustainable direction has the potential to have […]

The customer acquisition strategy for an organization is most effective if informed by insights into which customers would provide the most value, how much it would cost to acquire those customers, and what is the probability of success for acquiring a particular customer. While it is not tractable to do such analysis at the individual […]

Breast cancer was the most common cancer in 109 countries including Canada (excluding skin cancer) in 2020 (WHO). Early detection is critical in prognosis. The standard-of-care in early-stage breast cancer is breast conserving surgery (BCS), typically followed by radiotherapy and/or chemotherapy and/or endocrine therapy. The gold standard for margin assessment for BCS is histopathology. Results […]