The projects aims to develop a method to block the Wnt16B protein known to cause cancer growth and development by using target specific Camelid IgG antibodies in cancer cell culture that overexpresses Wnt16B. The Camelid antibodies programed to block the Wnt16B protein will be assessed for efficiency on how well they are able to block […]

This project will study how underbody components (tailpipe, muffler, rear fascia brackets and spare wheel compartment) withstand thermal loads over time through the use of a heat-transfer model (using RadTherm simulation package) of the vehicle under investigation as well as the first-order Taylor Series expansion. The Taylor Series will be used to calculate the sensitivity […]

Riverbank erosion is a major concern around the world, caused by high river floods. Occurrences of intense floods in rivers, attributed to climate change, such as the recent (July 2023) incidents of cloudbursts and accompanying riverbank washouts in several parts of northern (Himalayan) India provide glaring examples. Protection against riverbank erosion is, therefore, a formidable […]

Atherosclerosis is a chronic disease of the cardiovascular system that involves hardening of arteries due to the deposition of plaque [1]. Atherosclerotic lesions in different locations may lead to a variety of diseases such as Coronary Artery Disease, Cerebrovascular Accident and Peripheral Artery Occlusive Disease which should be detected at early stage [2, 3]. To […]

Proteins are large molecules found in all tissues they are composed of amino acids. Proteins perform most of the function in our bodies. Diseases are the result of changes to specific amino acids in proteins that result in alteration or complete loss of protein function. Pharmaceutical interventions in controlling or eliminating diseases depend on the […]

The project will develop and test VR scenarios for the assessment of selected AC tools and products. This will help AC develop more usable next-generation products.

Parkinson’s disease (PD) is increasingly prevalent, affecting ~170 per 100,000 Canadians annually. Currently, there is no cure for PD, warranting the investigation of potential new therapeutics. Photobiomodulation (PBM) is a low-level light therapy that has been proposed as an alternative treatment for neurodegenerative diseases, such as PD. However, there is a lack of data regarding […]

Humpback whales produce stereotyped, socially learned songs on their breeding grounds, yet little is known about song development outside the breeding season, or the effects of increased vessel traffic on humpback whale communication. With access to an extensive underwater Passive Acoustic Monitoring network along Canada’s BC coast, facilitated by the North Coast Cetacean Society and […]

Natural extracts have potential as anti-cancer therapeutics. Black Maitake mushroom extract (BME) is well tolerated, safe to be given as supplements over long period of time and has been approved from Health Canada for human consumption with NPN number. BME treatment has beneficial effect in patients as immunomodulator. We aim to provide scientific and preclinical […]

Cascades is one of the most renowned multinational Canadian companies with nearly 80 production units and employs more than 10,500 individuals spread across Canada and the United States. The company was founded in 1964 in Kingsey Falls, Quebec, and specializes in the pulp and paper production, processing and marketing in packaging and hygiene solutions made […]

Mechanochemistry uses physical, mechanical mixing in order to break and forms bonds in solvent-free conditions, which can yield different mechanistic outcomes compared to the traditional solution-based method. The highly concentrated mixing of reagents would be typically the last method thought to synthesize medium-sized ether rings, as the molecules require high dilution to promote ring closure […]

Social isolation and loneliness are serious public health issues with many adverse effects on individuals’ quality of life and well-being. Notably, these are growing problems in the aging population. Working from an existing prototype and extension of our previous Mitacs project, the main objective of this research project is to develop and optimize a personalized […]