Prediction of Complex Molecule Structures with HDX Mass Spectrometry-guided Molecular Dynamics Simulations Part II – Generalization and Parametrization

Hydrogen/deuterium exchange mass spectrometry (HDX-MS) is a powerful emerging experimental technique which provides important information about the solvent exposed area of complex molecular systems that is not readily available through existing technologies. HDX-MS can be applied to the specific cases of small molecules binding to protein systems, which is very important for the understanding, and […]

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A Mathematical Framework for Modelling Forest Fire Spread

Computer prediction models for forest fires are of great value to wildfire management. The goal of this project is to analyze the mathematical model used by the Wildfire Science Unit in their Prometheus fire prediction software package. In particular, the internship will work on the development of a robust software package which includes 3-D features […]

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Analysis and Classification of Data from 3D Morpho-Functional Assessments

The digital and bio-mechanical analysis of human motion is an attractive research field as it helps one understand and interpret pathologies affecting the body’s articular components. The goal of this project is to develop data analysis and automatic classification methods to differentiate between data from asymptomatic and pathological individuals. The data will be drawn from […]

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Computer Modelling of DC Plasma Torches with Draught Air in a Gasification Reactor

The use of plasma torches enables the gasification of waste into clean energy without producing any secondary residue. Because of the extremely high temperatures produced by plasma torches (more than 5,000 to 10,000 degrees Celsius depending on the type of gas used), the design of plasma torches and reactors presents new technological challenges to designers. […]

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Cryptographic Security Solution for Laptops

In their various versions (XP, 2003, Vista, Longhorn), Windows operating systems offer different cryptographic security technologies for data such as Encrypted File System and BitLocker. The capabilities of these tools depend on the presence of hardware modules for example, the Trusted Platform Module. The aim of this project is to complete a comprehensive study of […]

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Development of Production Planning Models

The Scotsburn Dairy Group produces over 300 ice cream products for many customers in a highly variable, seasonable market. Currently, no software packages exist in the market to help small to medium-sized dairies manage their production planning and scheduling. By working with Scotsburn, a production scheduling tool will be created which is tailored to the […]

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Effect of Pore Pressure Migration on Slope Stability: A Case History

A 150m high mine slope has been subject to movement, requiring the mine to reduce the slope steepness while extensive investigation and analysis is undertaken. This reduction in ore production has major implications for the economical viability of the mine. Golder & Associates, the engineer for the mining company, has numerically modelled the slope using […]

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Insurance Pricing with Proprietary Information

Information regarding the likelihood and severity of automobile accidents for individual insurance consumers enables insurance companies to price insurance policies. The more accurate and predictive the data, the more accurate and fair insurance prices are. Modern advances, such as telematics technology, allow insurers to improve the quality of their information. This improved information has an […]

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Lie Algebra Image Processing Applied to Intrinsic Optical Imaging

Optical imaging and the underlying image analysis has seen tremendous progress in recent years. Although it is now possible to perform multi-modal acquisition, the analysis frameworks for multi-modal data remain elusive. For example, the different scales and resolutions at which the images are taken require the use of mathematical techniques to deform, analyze and co-register […]

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Model Transformation

In recent years, model-driven approaches have been used to tackle problems of ever-increasing complexity. A crucial component is the modelling of model transformation. This project will develop theory, techniques and a prototype implementation of a model transformation system in partnership with Manyeta, a provider of high-performance support systems and content management solutions which help clients […]

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Monitoring Sleep-related Breathing Irregularities with Computer Vision Techniques

Sleep monitoring plays an essential role in the diagnosis of sleep disturbances. While the polysomnogram represents the gold standard, it has the disadvantage of assessing the patient’s sleep in an unfamiliar environment, usually a sleep clinic. This proposal targets the development of new computer vision-based methods for home-based sleep monitoring in partnership with Vigil Health […]

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Novel Approaches for Heart Failure Screening Based on Ballistocardiograph Signals

Identifying early onset of cardiac diseases is not easy and can be very expensive. For this reason, the first symptom of cardiac problems is often catastrophic for patients. The ultimate goal of this project is to produce a low-cost screening device that effectively identifies the presence of the disease early, allowing patients to take corrective […]

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