Mine waste rock drainage is one of the most challenging and lasting global environmental issues facing the entire mining industry, regulatory agencies and society as a whole. Mine drainage can be alkaline, neutral, moderately or extremely acidic and contains significant levels of sulfate, dissolved iron, and frequently a variety of heavy metals and metalloids. As […]

Episodic memory refers to an ensemble of memory processes and is the capacity to recollect where and when past events occurred, which involves subjective consciousness and a sense of time in retrieving past experiences. The hippocampus is essential for representing spatiotemporal context and establishing its association with the sensory details of daily life to form […]

Diabetes mellitus, a common metabolic disorder, exhibits neuropathic complications that can eventually lead to disabling pain (Todorovic 2015). This is attributed to hyperglycemia/high glucose resulting in neuronal hyperexcitability (Todorovic 2015). Importantly, diabetes-evoked neuronal hyperexcitability and neurotoxicity can be caused by alterations in voltage-gated sodium channel (VGSC) expression (Hong, Morrow et al. 2004), resulting in changes […]

Sudden Unexpected Death in Epilepsy (SUDEP), the commonest cause of death in epilepsy, is the most feared complication. SUDEP usually occurs following a seizure, most often in patients who are non-responsive to antiepileptic drugs. These patients are typically found dead in bed following respiratory apnea and cardiac arrest. Our group has shown that seizures in […]

Advances in Whole Slide Imaging (WSI) and Machine Learning (ML) open new opportunities to create innovative solutions in healthcare and in particular digital pathology to increase efficiencies, reduce cost and most importantly improve patient care. This project envisions the creation of new automated ML tools including the design of a custom Convolution Neural Network (CNN) […]

Social connections, especially satisfying romantic relationships, are vital for health and well-being. Yet, couples are spending increasingly more time apart, limiting opportunities for connection and intimacy. However, engaging in shared novel activities (i.e. self-expanding activities) can help couples connect and maintain their relationship over time. Indeed, couples who experience more self-expanding opportunities in relationships feel […]

The proposed project includes 2 objectives: (1) provision of high quality evidence on the effect of specific food sources of sugars on cardiometabolic risk factors by conducting multiple systematic reviews and meta-analyses (SRMAs), to address the effect of replacing sugar-sweetened beverages with either diet pop or water in a randomized controlled clinical trial, and to […]

A two-year study on brazing technologies used for sintered tungsten carbide tiles is proposed to address the following technical objectives: 1) brazing metallurgy for sintered tungsten carbide and substrate high strength steel, 2) adherence mechanisms between different braze compositions and carbide tiles, 3) brazing parameters for optimized brazed joint performance, and 4) the mechanical stresses […]

The current project will focus on understanding the behavior of one of the most important CANDU reactor components when it is subjected to the reactor environment. This study will develop a fundamental understanding of the X-750 material’s behavior resulting in innovative technologies that benefit the nuclear industry in Canada. In the short to medium term […]

The proposed research will focus on changes in cannabis use patterns and sources of supply following cannabis legalization, and on how these changes produce and/or reduce cannabis-related harm. The research will involve statistical analyses of Statistic Canada’s National Cannabis Survey (NCS). Some key areas of consideration will be: cannabis-impaired driving, cannabis dependence, and youth cannabis […]

“On-going coach and volunteer training are essential to providing high-quality, evidence-informed practices in sport settings. This study aims to extend Special Olympics Ontario and Special Olympics Canada’s online training platform for coaches and volunteers by working with athletes with intellectual disabilities, current Special Olympics coaches, and families of Special Olympics athletes. An iterative process will […]

Our aim is to use machine-learning to improve treatment of post-surgical pain in children and adults. Most people addicted to opioids were initially exposed through the treatment of pain from trauma and/or surgery. The opioid crisis is reaching the pediatric population, in whom effective post-surgical pain management, with less reliance on prescription of opioids, is […]