The development of single-cell RNA-sequencing methods for identification of biomarkers and therapeutic targets in leukemic stem cells

Targeted cancer therapies have significantly improved the treatment of leukemias, but emergence of treatment resistance and subsequent cancer relapse significantly reduces patient survival. This relapse is primarily caused by the inability of current therapies to eradicate leukemic stem cells. It is currently extremely challenging to study these stem cells, due to its rarity in patient […]

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TARGETING CANCER TUMORS USING A NATURALLY REFINED PARASITE HOST ANCHOR PROTEIN

In this project we will combine knowledge from two different research fields, namely parasitology and cancer biology, to develop a novel approach to target a variety of cancer tumors with high specificity. The malaria parasite P.falciparum has evolved a protein (VAR2CSA) that allows infected human blood cells to bind a sugar structure called CSA on […]

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Developing an Indigenous-led ‘conservation economy’: Ecosystem service synergies and trade-offs from shellfish aquaculture in British Columbia’s Great Bear Sea

Without careful management, the growing number and intensity of human activities can negatively affect ecosystem health and cause conflict between users. Recognizing the need for integrated management, the Province of British Columbia and 18 Coastal First Nations collaborated to develop an integrated spatial Marine Plan for the North Pacific Coast. A critical part of implementing […]

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Applied Mineralogy for Improvement of Sensor-based Sorting of Bulk Ores

The project focuses on gold deposits in the Arequipa region of southern Peru which are presently being exploited by artisanal and small-scale miners (accounting for 11-14% of Peru’s gold production). The proposed research includes a detailed mineralogical study of the gold mines and the ore concentrates, which have not been previously investigated. The objective is […]

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Applied Mineralogy for Enhanced Processing of Gold Ore from Artisanal Mining in the Arequipa Region, Peru – Year Two

The proposed research has the objective of applying detailed mineralogical research to aid the multidisciplinary development of high speed sensors for real-time ore sorting applications. MineSense Technologies Ltd. is a mining technology company that develops such sensors and while they have successfully demonstrated the application of its core technologies to distinguish ore from waste material, […]

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En Route to 5G: Long-term Evolution (LTE) Enhancements for the Internet of Things (IoT)

Cellular wireless communication has reached a level of coverage and reliability that it is considered a commodity. However, the dramatic increase in Internet traffic to and from wireless devices poses significant challenges for network operators. While the current growth of traffic is mostly due to consumers communicating more frequently and larger amounts of data over […]

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En Route to 5G: Long-term Evolution (LTE) Enhancements for the Internet of Things (IoT) – Year Two

Cellular wireless communication has reached a level of coverage and reliability that it is considered a commodity. However, the dramatic increase in Internet traffic to and from wireless devices poses significant challenges for network operators. While the current growth of traffic is mostly due to consumers communicating more frequently and larger amounts of data over […]

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Long-Term Ecosystem Monitoring of the British Columbia Coast across a Gradient of Human Stressors

Proposed developments (pipelines, super-tankers) along the coast of BC have the potential to negatively impact (shell)fisheries. Direct monitoring of fisheries can only detect negative impacts which have already occurred; therefore, indicator species (meiofauna) and environmental variables are monitored to detect disturbances before productivity is impacted. Our project will monitor intertidal ecosystems (numerous species and environmental […]

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Long-Term Ecosystem Monitoring of the British Columbia Coast across a Gradient of Human Stressors – Year Two

Proposed developments (pipelines, super-tankers) along the coast of BC have the potential to negatively impact (shell)fisheries. Direct monitoring of fisheries can only detect negative impacts which have already occurred; therefore, indicator species (meiofauna) and environmental variables are monitored to detect disturbances before productivity is impacted. Our project will monitor intertidal ecosystems (numerous species and environmental […]

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Stochastic Strategies for Addressable Advertising

Recently, the nature of media advertising has changed dramatically due to the introduction of highly efficient addressable advertising models. The latter have the ability to deliver different ads during one advertising spot to the viewers of same network, depending on household demographic profiles. The new models provide industry with the opportunity to maximize advertising revenue […]

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Stochastic Strategies for Addressable Advertising – Year Two

Recently, the nature of media advertising has changed dramatically due to the introduction of highly efficient addressable advertising models. The latter have the ability to deliver different ads during one advertising spot to the viewers of same network, depending on household demographic profiles. The new models provide industry with the opportunity to maximize advertising revenue […]

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Design and Control of a Reconfigurable Packaging System

DCZS Intelligent Systems Inc. focuses on providing solutions for industrial automation as well as on facilitating the need of research facilitates and universities. DCZS is currently developing a Box Packaging Automation System (BPAS), targeting the growing needs in packaging/assembling processes in industry. Currently, BPAS is designed based on certain box packaging style and limited size […]

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