Dynamics of single P. aeruginosa cells under shear during biofilm formation

The proposed project involves the use of a combination of two techniques i.e., rheology, confocal microscopy and image analysis, aimed at understanding the physics of bacterial cells at interfaces. Given the fact that the interactions and the interplay of forces are complicated at interfaces, the proposed study can provide significantly valuable insights into the dynamics […]

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A Comprehensive investigation for Simulating SVOC’s Adsorptive Behavior in an Experimental Chamber: effect of humidity and adsorptive site’s accessibility

This study investigates the adsorption of semi-volatile organic compounds (SVOCs) in an experimental chamber, focusing on humidity effects and adsorptive site accessibility. Essential for workplace safety in indoor settings, this research tackles the complex dynamics of SVOCs like phthalates and flame retardants, often found in low concentrations but posing significant health hazards. The project highlights […]

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Mathematical modeling of vertebrate retinal cone photoreceptor patterns

Cone photoreceptors are specialized cells in the retinas of vertebrates that absorb light to permit daylight vision. Two major morphological types exist: single cones, which are circular in cross section, and double cones, which consist of two apposed cones with elliptical cross section. In many vertebrates, cones are organized into repeating, lattice-like mosaics. The two […]

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Specificity of the cAMP-PKA signalling pathway during thermotolerance in Saccharomyces cerevisiae

The proposed research project aims to investigate how Saccharomyces cerevisiae, a microorganism commonly used in the food and biofuel industry, responds to changes in temperature and manages to withstand high temperatures. Yeast cells face various types of stress as the environment conditions change, both in natural situations and during industrial processes. S. cerevisiae has developed […]

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Development of targeted delivery system for saRNAs using SNAP tag-based antibody fusion protein to treat triple-negative breast cancer

Triple negative breast cancer (TNBC) is a highly invasive and heterogenous disease that does not express oestrogen receptor and progesterone as well as the human epidermal growth factor receptor-2 and accounts for approximately 20% of all breast tumors. Its heterogenicity makes unlikely to reach the complete TNBC patient population with a single therapeutic agent. Therefore, […]

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Photogrammetric speech motor control assessment

Speech sound disorders (SSDs) are an umbrella term for a range of speech difficulties characterised by a constellation of deficits. Identifying SSD subtypes can be supported by objectively analysing the child’s speech and facial movement patterns (kinematics). However, these movements can only be precisely and specifically measured using specialised instrumentation and software limited to the […]

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Disaster Management and Informal Settlements in India

The most recent flood in Ahmedabad, India occurred in September 2013, when 50,000 people were displaced from low lying areas of the state. The World Bank report warns that the poor living in informal settlements, such as coastal slums in India, are the most likely to be killed or harmed by extreme weather linked to […]

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Palmitoylethanolamide as an intervention for preventing schizophrenia in a maternal immune activation rodent model

The major problem with intervention for schizophrenia is the inability to treat all symptom categories (positive, negative, and cognitive) sufficiently. The need to test new novel therapies is crucial, which may prevent the onset of this debilitating disorder. Since intervention is limited to individuals at high risk, researchers have turned to animal models to test […]

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Synthèse et étude structure-activité des bactériocines produites par Lacticaseibacillus paracasei CNCM I-5369

ace à la propagation alarmante des bactéries résistantes aux antibiotiques, le développement de nouveaux antimicrobiens avec des modes d’action innovateurs est devenu une priorité mondiale. Parmi les différentes alternatives, les peptides antimicrobiens d’origine bactérienne comme les bactériocines sont très prometteurs. Ce projet s’intéresse particulièrement à cinq bactériocines produites par la bactérie Lacticaseibacillus paracasei qui ont […]

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Genome engineering of large chromosomal deletions

Cancer is associated with an accumulation of alterations in genes that confer the ability of cancer cells to grow uncontrollably. These alterations can contribute to increased deleterious function or loss of function of genes that normally regulate cell growth. Genes in our cells are organized on chromosomes which duplicate every time a cell divides. In […]

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Fabrication of 1 D semiconducting microstructures using lithography

Modern technology relies heavily on semiconductor materials, from smartphones to solar panels. Among semiconductor materials, one-dimensional (1D) materials, such as nanowires and nanoribbons, offer exceptional electronic and optical properties. To realize the full potential of these 1D materials, it is imperative to control their synthesis and manipulate their structures precisely. In this project, we aim […]

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