For the past several years, advances in cryogenic-electron microscopy (cryo-EM)have led to a revolution in structural biology, for which the Nobel Prize in Chemistrywas awarded in 2017. To enable the 3D reconstruction of atomic structures, thedevelopment of mathematical methods has been instrumental to address thesample size, noise, and geometric complexity inherent with cryo-EM data. Tosignificantly […]

Le projet de maîtrise de la candidate a pour objectif de fournir les connaissances et balises nécessaires au développement d’un outil de suivi de la vache en période de transition. Cet outil abordable et efficace sera développé à partir de la composition en acides gras (AG) du lait. La période de transition étant reconnue comme […]

The project aims to identify the interdependence that exist between epigenetic modifications that regulate gene expression, as well as their susceptibilities to permanent disruption following errors in the embryonic program. We use an innovative embryonic stem cell model in which the expression of an epigenetic enzyme responsible for DNA methylation can be controlled. We will […]

Manipulation and characterization of ultrafast optical signals are fundamental procedures for a wide range of applications, including telecommunications, biology, quantum information science, spectroscopy, and atomic and molecular physics. In this context, the so-called theory of space-time duality offers a powerful framework for the development of important optical signal processing functionalities. One of its key elements […]

Human trafficking and sexual exploitation are serious and complex issues affecting millions of children around the world. Unfortunately, scientists, Child protection workers (CPWs), law enforcement personnel, and other experts are currently struggling to effectively prevent these crimes and ensure the rehabilitation of vulnerable children. One of the main hurdles impeding their efforts is the current […]

Through unknown mechanisms, parent-of-origin-specific methylation marks on one allele of imprinted genes are able to escape the embryonic reprogramming wave occurring during the first week of development and retain their profiles via DNA methylation maintenance activity. Failing to maintain proper genomic imprinting patterns during the embryonic reprogramming leads to various abnormal developmental delay. What remains […]

L’objectif des travaux de recherche entrepris lors du séjour à l’étranger est de de mieux comprendre comment le contrôle en temps réel du réseau de drainage (contrôle intelligent des infrastructures de drainage) influence la conception des ouvrages de contrôle à la source (comme les infrastructures vertes visant à faciliter l’infiltration et l’évaporation de l’eau pluviale […]

Climate change has become a major concern over the past decades. In this context, one of the biggest issues is the amount of carbon dioxide (CO2) produced every year around the globe. In response, researchers have discovered creative solutions to recycle CO2 via a process commonly known as CO2 fixation. More recently, the use of […]

The Feline Grimace Scale is a validated tool that uses changes in facial expressions for acute pain assessment in cats. The tool is a valid, reliable, sensitive and specific for feline acute pain recognition for various types of painful conditions (www.felinegrimacescale.com). The aim of this research project is to assess the effects of sedation and […]

The agglomeration of nanoparticles under flame conditions is numerically simulated. The focus is placed on the interaction forces between particles. These forces are suspected to play an important role on the agglomeration rate, agglomerate’s geometry, and particle size distribution. This is particularly important in the context of aggregates (chemically bound nanoparticles) or agglomerates (physically bound […]

Neuroprostheses interfacing with brain and spinal tissue are in rapid development and are being applied to clinical treatment of paralysis after spinal cord injury stroke and other neurological disorders. We have developed a versatile intelligent neuroprosthetic agent, a Gaussian Process (GP)-based Bayesian Optimization (BO) approach. We have further laid the theoretical groundwork to cover larger […]

My proposed project consists in completing the final chapters of my doctoral dissertation: The World as Sacrament: The Eucharistic Ontology of Maximos Confessor. In essence, I argue that Maximos’ insistence that all things are created from God (ek theou) according to (kata) the Logos offers a powerful example of sacramental ontology – that is, a […]