Medicinal Chemistry Studies on Small Molecule Glucocerebrosidase Inhibitors

The objective of this internship is to create new chemical compounds that can be used to further our research and understanding of a human enzyme known as GBA2 – implicated in several debilitating diseases and signalling pathways in the body. These compounds would not only serve as tools to probe GBA2 for additional information but […]

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Consequence assessment of potential tailings storage facility failures within the Canadian context

Recent catastrophic tailings storage facility (TSF) failures have resulted in immense societal, environmental and economic losses. Currently, research on TSF risk is primarily focused on the technical reasons for failure or post-failure environmental damages. Furthermore, limited research explores the financial, environmental and social consequences of potential TSF failure within potential tailings inundation zones. This project […]

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Twitter Data Processing

Given the plurality of voices available on the I nternet, it is often difficult to estimate the level of expertise of the individuals that one encounters in cyber-space. On the other hand, it is also difficult for any individual expert to establish their credibility in this sea of screaming voices. Therefore, it is desirable to […]

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Investigating the effect of the Virtual Meditative Walk on brain in chronic pain conditions: A longitudinal fMRI study

The Virtual Meditative Walk (VMW) (1) is a well-developed therapeutic protocol that can be used alone or in combination with the Mindfulness-Based Stress Reduction techniques in an Immersive Virtual Reality (IVR) environment. It has been shown to be effective in reducing pain levels in patients with chronic pain (CP); however, little is known about how […]

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Investigating the effect of the Virtual Meditative Walk on brain in chronic pain conditions: A longitudinal fMRI study – Year two

The Virtual Meditative Walk (VMW) (1) is a well-developed therapeutic protocol that can be used alone or in combination with the Mindfulness-Based Stress Reduction techniques in an Immersive Virtual Reality (IVR) environment. It has been shown to be effective in reducing pain levels in patients with chronic pain (CP); however, little is known about how […]

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Understanding the Operational, Human, and Policy Implications for a Roadmap to Canada’s Next Generation 9-1-1 Services

The project will create a research-based strategic plan and roadmap that describes when and how to best introduce NG-911 services in British Columbia. The research needs to consider the unique BC context including review of current legislation, our emergency response structures and practices, current technologies, societal expectations and political norms. The work also needs to […]

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Market Analysis of Next-Generation Lithium Batteries

Lithium-ion batteries have revolutionized electronics over the past two decades, however, they do not have sufficient energy density to meet the long-term needs of society, such as the development of electric vehicles. This formidable challenge has driven research into many new battery technologies with different chemistries and configurations, but it remains unclear which technology is […]

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Inclusive Resettlement: Integration pathways of resettled families with disabilities in Germany and Canada

My internship will take part of a comparative study aiming at exploring structural conditions and individual integration pathways of resettled refugees with inter-sectional risks of exclusion in Canada and Germany. The study consists of 1) a scoping literature review on resettlement pathways of families with disabilities and 2) mix-method data collection from resettled refugees with […]

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Water-based “Ink” Formulations for Metal 3D Printing

Rapidia has developed a water-based approach to metal 3D printing that is faster, simpler, and more cost effective than the current systems on the market. This novel approach enables printed parts to be sintered directly, eliminating the time- and chemically- intensive intermediate de-binding step required for other processes. In order to implement this technique, the […]

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Evaluation, optimization and modeling of sequencing batch reactors (SBR) operation for treatment of municipal wastewater

Sequencing batch reactor (SBR) is an activated sludge process that has been used successfully in municipal and industrial wastewater treatment. SBR process is operated in a batch mode where different batch phases run successively in a single tank or several tanks operating in parallel. Many studies on real-time control strategies have been employed to check […]

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Synthesis and characterization of a new generation of bone targeting anabolic prodrugs

Prostaglandin E2 stimulates bone formation in vivo and exerts its effects through the EP4 receptor. Unfortunately prostaglandin E2 and agonists for the EP4 receptor also cause unacceptable systemic side effects which have limited their clinical use as anabolic agents. We developed novel bone-targeting prodrugs that can deliver EP4 agonists selectively to bone and liberate active […]

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Synthesis and characterization of a new generation of bone targeting anabolic prodrugs – Year two

Prostaglandin E2 stimulates bone formation in vivo and exerts its effects through the EP4 receptor. Unfortunately prostaglandin E2 and agonists for the EP4 receptor also cause unacceptable systemic side effects which have limited their clinical use as anabolic agents. We developed novel bone-targeting prodrugs that can deliver EP4 agonists selectively to bone and liberate active […]

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