Investigating astrocyte responses in brain metastasis of HER2-positive breast cancer

Brain metastasis of breast cancer has a very poor prognosis in patients. Treatment options are limited because the blood-brain-barrier prevents drugs from entering the brain. Importantly, we are lacking information on how brain cells are supporting the growth of metastatic breast cancer cells. Using HER2-positive breast cancer cells isolated from a patient brain metastasis the […]

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Soil-reinforcement interaction of a novel type of geogrid-geotextile composite for road applications: Experimental and numerical studies

Incorporating geosynthetic layers on top of the subgrade layer provides more stability and serviceability. That becomes a must when the subgrade layer is classified as a problematic soil. With the traditional method, two layers of geosynthetic are adopted: a geogrid for reinforcement and a geotextile for filtration. Placing these two materials in this manner is […]

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Development in the fabrication of oxide nanowires used in biosensors

Detection and quantification of biological species are critical to many areas of healthcare and life science, either intending to diagnose diseases or discover and screen new medicine molecules. Central to detection are the biosensors that generate a signal associated with the selective recognition of a species of interest. Nanostructures, such as oxide nanowires with large […]

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A soft magnetic small-scaled robot for biomedical applications

This study aims to develop a soft and flexible magnetic millirobot based on elastic and biocompatible polymers that can generate voltage as it moves. By using this proposed millirobot, locomotion efficiency can be increased with a decrease in resistance under challenging and harsh conditions in stomachs and digestion systems. In addition, it can serve as […]

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Performance Analysis of Northern Infrastructure Affected by Climate Change

In this project, considering the rate-dependent behavior of permafrost, a multiphysics-based hazard ??assessment tool will be developed to investigate the life-cycle performance of infrastructure subject ?to ?different seasonal climate projections and climate change scenarios. For this purpose, first, an ?advanced thermo-elasto-viscoplastic (TEVP) constitutive model is being developed based ?on the ?framework of critical state soil […]

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Pathology and disease diagnosis using artificial intelligence and machine learning: Supervised and unsupervised deep-learning based methods on data from medical imaging procedures and patient chart analysis

Machine learning applications in healthcare have shown excellent inroads in medical imaging sciences in recent years. Our research aims to improve upon and open up doors into several different pathology diagnosis applications using artificial intelligence. Contemporary research into some of these applications has shown better diagnostic capacity than expert-level clinicians. Our research into artificial intelligence […]

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Guideline for Empirically-Based, Integrated Design Process Oriented Sustainable Architecture in Zone 2b (Winnipeg, MB, Canada)

This research project proposes to gather sustainability strategies from different building-performance certification strategies and apply them in combination with climate data for the specific, and extreme zone in which Winnipeg is classified. This localized lens will allow refinement of strategies, which will be tested through digitally modelling 3D case studies to analyze different approaches to […]

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Anomaly detection tool for gas turbine condition monitoring under variable operating and environmental conditions

Different industries have widely employed condition monitoring to evaluate their system’s health. For gas turbines, current methods have limitations related to certain operating and environmental conditions and are mainly based on supervised approaches requiring annotated data that is hard to acquire. This project will focus on developing an unsupervised anomaly detection mechanism that alarms users […]

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Smart Vertical Farming

The Smart Vertical Farming project will utilize smart sensor technologies and advanced computing to optimize indoor growing conditions for plants. Researchers will monitor inputs such as fertilizer levels, soil conditions, lighting, temperature, humidity and CO2 levels in real-time and make correlations to the plant growth using cameras to measure foliage density, colour and health. Advanced […]

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