Autonomic, cardiovascular, respiratory, muscle oxygenation regulation during postural transitions and acute exercise in females and males living with frailty

This research aims to: (1) determine how the brain, heart, vessels, lungs, and muscle oxygenation regulation in female and male frail older adults. In study #1, participants will perform three postural transitions: (a) sit-to-stand, (b) lie-to-stand, and (c) lie-to-sit, and three identical constant workload walking tests. The autonomic (brain, e.g., sympathetic and parasympathetic activity), cardiovascular […]

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Efficient, cost-effective purification of soybean peroxidase for industrial applications

Pharmaceutical contamination of water systems poses direct threats to human health and the environment. Unfortunately, wastewater treatment plants are not always capable of sufficiently removing pharmaceutical contamination, particularly where drugs are disposed of in high concentrations – such as pharmaceutical manufacturing facilities. When some residual drugs are released into the environment they can persist and […]

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Design and fabrication of metamaterial energy absorber, generator, vibration isolator

Our main aim is to design and fabricate lightweight mechanical structures to show high energy absorption capacity with as low as initial reaction forces, electricity generation via embedding smart materials (piezo patches), and isolate external dynamic excitations. The designed mechanical structures could be applied in the automobile and motorcycle industries. In a car crash, the […]

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Commercialization strategies for academic drug discovery projects: From bench to start-up

Translation of scientific bench-top discoveries into a commercial enterprise can be one of the hardest transitions for academic groups. Additionally, there are very few therapeutic options for neurodegenerative diseases, and a great need exists for the development of new drug candidates to treat diseases, such as amyotrophic lateral sclerosis. Our proposal seeks to continue with […]

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Autonomous Cognitive Examination: A Validation Study

Timely diagnosis of dementia is a public health challenge within Canada. It is hoped that machine-learning empowered cognitive examinations might improve Canada’s response to the dementia population. This study proposed the validation of an automated cognitive examination, the Autonomous Cognitive Examination, which uses machine learning to evaluate users to evaluate previously difficult to assess inputs […]

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Development of a support tool for product maintenance using augmented reality

Augmented Reality (AR) provides real-time interactive instructions to improve efficiency and accuracy of product maintenance processes. Although different methods have been proposed for the AR-based product maintenance, there is a lack of methods of automatic product disassembly and assembly planning under the AR environment. This project develops an AR-based tool for product maintenance instructions. The […]

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Transformation of healthcare data management using blockchain technology

The healthcare industry is focusing on utilizing emerging technologies to make healthcare systems secure, interoperable, and efficient. Blockchain technology offers promising features, such as immutability, security, traceability and decentralization, appropriate for clinical healthcare interoperability and data sharing. This project is part of Lab2Market program, which provides a commercial opportunity to utilize blockchain technology, a new […]

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A Machine Learning-based Tool for Generation and Evaluation of Product Design Concepts

The global competitive market requires products to meet the high customer satisfaction, low production cost and short development cycle. Product design searches for potential solutions of products to meet customer requirements based on design constraints and technical details. As a large number of possible concepts have to be explored in the design process, applying the […]

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Development of a user interface to setup 3D printing parameters

Products have to meet high customer satisfaction standards, low production costs in order to compete in the global market. Comparing with conventional production techniques, the additive manufacturing (AM) technology can construct complicated forms with more efficiency. In order to produce high quality 3D printed parts, the appropriate selection of printing parameters is crucial. Advanced parameter […]

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Integrating Local Knowledge and Emergency Preparedness: Improving Resilience Through Collaboration

The project seeks to create a framework for community engagement that centers around Indigenous knowledges and emergency preparedness. This framework will be based upon a review on the existing research on how local knowledge from Indigenous communities has been integrated with existing emergency preparedness models. Existing emergency preparedness and community resilience protocols were developed primarily […]

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Impact of type I interferon exposure on interferon stimulating genes (ISGs) in the female genital tract

Globally the rate of Human immunodeficiency virus (HIV) transmission is on the rise. This is quite disturbing and hence there is the urgent need to understand and develop better preventive strategies. A canonical antiviral molecule called “Type 1 interferon” is known to interfere with viral replication. In a large-scale cytokine analysis of South Africa tenofovir […]

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