Functional long non-coding RNAs in the 3D structure of the genome

Previous research has shown that most of the mammalian genome is transcribed, while most mammalian transcripts do not code for proteins and may instead be functional themselves. Non-coding RNAs play critical roles in some of the most fundamental processes in molecular biology. The vast majority of mammalian non-coding transcripts are constituted by long non-coding RNAs […]

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Hyphenated and Whole: Forms, Aesthetics, and Sociology in Korean-Canadian and Global Korean Literatures

My doctoral project aims to fill a common and critical gap between Asian-Canadian literature and global Korean-diaspora studies by undertaking the necessary examination, translation, and preservation of Korean-Canadian literature. As part of this larger project, I propose to develop my understanding of modern Korean literature, including its development, forms, and socio-cultural politics, to shape a […]

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Design and Exploration of a General Purpose Stochastic Computing Processor

The rise of Internet of Things (IoT) with millions of edge devices created per year drives the need for computing platforms that have lower power, better fault tolerance and greater computing flexibility. With more and more novel applications and algorithms being rapidly deployed, the traditional approach of using custom hardware to achieve a low power […]

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Downstream purification of RNA therapeutics

Gene therapy is an expanding field that shows promise in the long term treatment of many genetic disorders. CRISPR-Cas9 technology is one way of editing the existing genome when trying to treat genetic disorder, or engineering genetic therapeutics. One area of interest is RNA therapeutics based on this technology. The Zydney and Salis lab groups […]

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Properties and behaviours of Mesenchymal Stem Cells in response to lung microenvironment in human Acute Respiratory Distress Syndrome

Acute respiratory distress syndrome (ARDS) is a life-threatening condition with a high mortality. Currently, there are no proven pharmacological therapies available for the management of ARDS patients. Mesenchymal Stem Cells (MSCs) have been shown to be interesting candidates for treating ARDS. But their therapeutic effects as demonstrated in animal models and clinical trials have been […]

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Long non-coding RNAs (lncRNAs) in liver fibrosis in diabetes

As diabetes continues to rise globally, the risk of developing chronic diabetic complications greatly increases. Among these complications, non-alcoholic fatty liver disease (NAFLD) is a serious liver disease that can contribute to major scarring of the liver and this may ultimately lead to liver failure. To develop a better understanding of the processes involved in […]

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Impact and blast resistance of bare and concrete-infilled FRP tubes

Impact and blast loads are two severe dynamic loads that need to be investigated for any industrial and structural applications. Recently, Fiber reinforced polymer (FRP) tubes have been used in different electrical applications as electrical conduit systems, in addition, FRP tubes are used in structural applications in the form of Concrete-Filled FRP tubes (CFFT) members […]

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EU Institutions Promoting High-Skilled Migration for Innovation & Growth

This project seeks to understand the role different European Union (EU) institutions play in the global competition for highly-skilled migrant professionals. While EU member states still retain sovereignty over the long-term admission of third country nationals, the EU Commission, Council and Parliament have started to propose and push policy initiatives related to high-skilled migration. Triggered […]

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The Role of Values and Beliefs in Dried Fish Production: A Focus on the Well-Being of Producers in the Indian Sundarbans

Values and beliefs within social-ecological systems (SES) are a fundamental aspect of perception and cognition, which have largely been neglected within the social-ecological systems literature. The purpose of this research is to understand the values and beliefs of dried fish producers and how they contribute to the producers’ well-being in Sundarbans region, West Bengal, India. […]

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Nano Processing Technique for Flexible Electronics

Conductive polymer nanocomposites have become increasingly popular due to the combined flexibility and low cost. The presence of a conductive filler network, which is reconfigurable by applied strain, can be used in sensors. The materials to be developed are ideal for the biomedical field and wearable electronics where flexible non-invasive devices can be worn outside […]

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Storm Shelters Resilient to Changing Canadian Climate

The recent tornado that hit the Ottawa-Gatineau region in September 2018 damaged hundreds of homes and many hydro poles/towers leaving more than 450K customers without power. In Canada, the average annual loss due to local events (i.e. thunderstorms, tornados and downbursts) is in the order of $200M. The number of these extreme local events has […]

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