Resilience of modern skyscrapers subject to natural hazards

The structural performance of skyscrapers subjected to natural hazards such as strong winds and earthquakes has significant effects on the resilience of a city because of the recent boom in the construction of skyscrapers around the world. However, resilience is currently not explicitly considered in the design of tall buildings. Studies show that modern tall […]

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Resilience of modern skyscrapers subject to natural hazards – Year two

The structural performance of skyscrapers subjected to natural hazards such as strong winds and earthquakes has significant effects on the resilience of a city because of the recent boom in the construction of skyscrapers around the world. However, resilience is currently not explicitly considered in the design of tall buildings. Studies show that modern tall […]

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Non-Traditional Modulation Schemes

The need for more and more data rates is significantly increasing due to the newly introduced wireless/mobile applications and services. Traditional modulation schemes cannot provide satisfactory long-term solution to this problem. That said, non-traditional modulation (spiral-based modulation) comes into play as a strong candidate to solve the increasing data rate requirements problem. Spiral-based modulation exploits […]

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Development of Standardized Laboratory and Semi-Field Methods for Assessing the Risk of Pesticide Exposure to Megachile rotundata F.

Non-Apis bees are now recognized as significant pollinators. For most crops visited by bees, pesticides are used for pest management, and there is concern about the potential negative effects of pesticides on wild and managed bees. Most toxicity studies involving bees have focused on honey bees (Apis mellifera), partially because honey bee data are required […]

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Development of Standardized Laboratory and Semi-Field Methods for Assessing the Risk of Pesticide Exposure to Megachile rotundata F. – Year Two

Non-Apis bees are now recognized as significant pollinators. For most crops visited by bees, pesticides are used for pest management, and there is concern about the potential negative effects of pesticides on wild and managed bees. Most toxicity studies involving bees have focused on honey bees (Apis mellifera), partially because honey bee data are required […]

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Development and Delivery of Inhibitors for Viral Pathogenic Deubiquitinases

In human viral diseases, misbehaviour of the cellular machinery utilizing ubiquitin is frequently observed. Ubiquitin is a small protein that attaches to target proteins in human cells and signals for their destruction. Human deubiquitinases are enzymes that remove ubiquitin to keep protein levels in balance. Viral pathogens have evolved proteins that mimic human deubiquitinases to […]

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Development and Delivery of Inhibitors for Viral Pathogenic Deubiquitinases – Year Two

In human viral diseases, misbehaviour of the cellular machinery utilizing ubiquitin is frequently observed. Ubiquitin is a small protein that attaches to target proteins in human cells and signals for their destruction. Human deubiquitinases are enzymes that remove ubiquitin to keep protein levels in balance. Viral pathogens have evolved proteins that mimic human deubiquitinases to […]

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Versatile applications of a safe and efficient peptide in gene/drug delivery

Gene therapy is one of the most attractive new therapeutic strategies in the treatment of multiple diseases. However, to apply gene therapy in clinic, an efficient and safe delivery system must be developed to transport these therapeutic reagents to target organs. The existing gene carriers suffer from either high cytotoxicity or immunogenicity problems, which will […]

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New strategies to improve the use of the predatory bug, Orius insidiosus, to control Western Flower Thrips, Frankliniella occidentalis, in greenhouse ornamental crops

The proposed research will investigate how to improve the performance and economic sustainability of Orius insidiosus as a biological control against Western Flower Thrips in greenhouse ornamental crops. New strategies to increase the efficiency of O. insidious will be investigated through the use of banker plants, supplemental food, and the use of lures. The project […]

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Neural and autonomic correlates of post-traumatic stress disorder during processing of trauma-related stimuli

Post-traumatic stress disorder (PTSD) emerges after the exposure to an event that elicits horror or helplessness, including threat of injury or death to one’s self or another person. Community-based studies have evaluated its occurrence with a lifetime prevalence of 9.2% in the Canadian population. This research project aims to develop innovative, neural-substrate based, and novel […]

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Development of Cell-Based Functional Assays to Accelerate Commercialization and Therapeutic Application of Recombinant Antibodies

Antibodies are the fastest growing segment of the pharmaceutical market, and with modern engineering technologies antibodies can be programmed to target devastating diseases. Within the immune system, antibodies fight invading bacteria and viruses. High-quality synthetic antibodies directed to disease-related targets have immense therapeutic potential. Development of cell-based assays to enable rapid identification of functionally active […]

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