Improved method of donor kidney storage at subzero temperatures

Currently, storage of donor kidneys at low temperatures is limited to 24 hours. If the storage time of donor kidneys could be extended, this would allow more opportunity to identify and prepare suitable recipients for this life-saving procedure. Our improved method of kidney storage at subzero temperatures will also allow patients at more remote locations […]

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Genetic variation in 9p21, dietary patterns and cardiovascular disease risk

Cardiovascular disease is a leading cause of death in Canadians and expected to claim nearly 65 000 lives in 2015. Approximately 75% of these deaths are preventable by having a healthier lifestyle, including a better diet. Another risk factor is having a family history of heart disease, mainly because of inherited genetic risk factors. A […]

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Flows of Water, Flows of People in Lao Cai, Vietnam

The Red River, flowing from China, runs through the northern border city of Lao Cai, in one of the poorest and most mountainous regions of Vietnam. A new expressway runs through Lao Cai and supports increased trade and investment. The economic growth draws in rural migrants, and also displaces people as it appropriates land to […]

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Spatial Optimization Modelling for China’s County-level Land Use Planning

Considering the research gap that there lack quantitative models and advanced techniques to solve the land spatial allocation problem in China’s county-level, my PhD project aims at developing spatial optimization models to assist land spatial allocation that reconciles the market value, social value and ecological value of land, land utilization zoning and boundary setting in […]

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Multivariate polynomial interpolation: efficient algorithms and applications

This research project aims at providing efficient methods to solve a mathematical problem which has practical applications in digital communication and online storage. In the domain of communications, these methods perform the decoding stage of some error-correcting codes, which are used to ensure reliable data transmission over an unreliable or noisy communication channel such as […]

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Human Performance of Finger Identification for Multitouch Input

The project first aims at developing a robust and low latency hardware system for identifying which fingers are in contact with a surface. The second objective is to implement and refine finger identification interaction techniques that would improve the interaction with touch surfaces (smart phone, tablets, tabletops). These techniques will be evaluated to state of […]

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Experimental and Numerical Investigations of a Rice Husk Pyrolysis Reactor

A rice husk pyrolysis reactor producing syngas and char was developed by GreenGenTech Energy Inc. (Ottawa, ON) and is currently being built and commercialized in China by a partner company called Ruizhantai. The reactor is fully functional and some sites have been running continuously for two years, although requiring skillful operation during start-up or when […]

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Fluorescence Image Enhancement for Digital Pathology (DP) Scanners

Fluorescence imaging is a powerful technique to focus and acquire high-resolution pathology images that contain rich sources of information that is useful for diagnostics in clinical trials to study possible disease such as cancer glands and tumors. Despite the high definition images, the collected images are severely contaminated with noise artifacts which make most feature […]

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Negotiating in the Shadows

The research will examine the way in which marginalized communities are able to negotiate access to essential conditions of life such as water and housing. Infrastructure development and consumption patterns have failed to adapt to rapid economic growth and urban expansion. This has created an inequitable rift between social groups, with marginalized groups such as […]

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Determination of stress-induced modifications to vaccine proteins by mass spectrometry

The therapeutic effect of a vaccine depends on its chemical composition, and in particular the integrity of its protein components. Conditions under which a vaccine is manufactured and stored can damage the proteins it contains; however, since proteins are structurally complex and reactive, their degradation during routine handling is unpredictable. In the project described here, […]

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Pharmacological and phytochemical characterization of immunomodulatory polysaccharides from American ginseng

Ginseng is a medicinal plant with a long history of traditional use. The medicinal properties of ginseng root have been attributed to two main classes of chemical compounds: ginsenosides and polysaccharides. While much is known about ginsenoside pharmacology, less is known about polysaccharide pharmacology. One of the most important properties of ginseng root polysaccharides is […]

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