Phytochemicals are secondary metabolites that offer biological activity to prevent degeneration of different non-communicable diseases such as type-2 diabetes (Stroke), cardiovascular disease, and cancer. Indigenous food crops are rich source of phytochemicals such as phenolic acids and flavonoids which have demonstrated some biological activities including antioxidant, anti-inflammation and anti-bacterial effect. This study aims to screen […]

CHORE aims at the design of a biohybrid synapse between biological neuronal cells and organic neuromorphic devices made of CHORE aims at the design of a biohybrid synapse between biological neuronal cells and organic neuromorphic devices made of a conjugated polymer-based hydrogel which is sentitive to ions released by ther biologtical counterpart. The project icludes […]

La bioréparation d’une fissure d’un béton a pour but de la colmater pour empêcher le passage de l’eau. Actuellement, deux types d’ouvrages sont principalement ciblés : les ouvrages hydrauliques et les voutes des tunnels en béton. Le colmatage est accompli en injectant, dans la fissure, un liquide nutritif contenant des bactéries. Ces bactéries produisent du […]

Plants face various challenges when they grow. They are attacked by numerous diseases and this can negatively affect their growth and productivity. Plants have complex means of defending against diseases. In order to create disease resistant crops it is important to first understand how plants are able to defend against these diseases and understand how […]

Chez les vertébrés, le mode de reproduction le plus fréquent est la reproduction sexuée, ce qui implique la fusion de gamètes, soient l’ovule et le spermatozoïde, provenant de deux parents de sexes opposés. Dans certains cas rares, le mode de reproduction d’une espèce peut devenir asexuée c’est-à-dire, une reproduction par soi-même. Chez les vertébrés, ces […]

My research focuses on understanding the mechanism of action of a new class of tumor suppressor genes using the well established round worm (nematode) model system. Previously published data from Gupta and Chamberlin lab have shown that deleting the function of these genes causes excessive proliferation of cells (similar to cancerous growth). To further understand […]

Skeletal muscle, an essential organ system making up 30-40% of total body mass, is unique in that it allows for the body’s voluntary movement. It is solicited and stressed daily and consequently possesses the remarkable ability to regenerate in response to injury due to a special population of cells named muscle stem cells (MuSCS). At […]

Our goal is to employ a host of new compounds, made by the applicant in her lab in Brazil, for drug discovery studies at the University of Toronto. Specifically, the host uses a technique called Nuclear Magnetic Resonance (NMR) to obtain signatures of drugs or ligands. These signatures can identify those compounds which bind strongly […]

A human protein “interleukin-2” plays a key role in immunity. The target of this project is to modify this protein, triggering more immune cells in body, and hence enhancing body defense. At first, the intern will produce normal interleukin-2 in bacteria. The protein will then be mixed with the immune cells. Increase in cell amount […]

The heart is a complex organ that pumps the equivalent of an Olympic-sized swimming pool of blood to the body each day. To accomplish this incredible feet, millions of cells must work together in a coordinated manner, enabled by tight connections between their electrical and mechanical activity. In cardiac diseases these connections are disturbed, which […]

Yeast is a single celled micro-organism that converts carbohydrates to carbon dioxide and alcohols through the process of fermentation. Yeast is very useful in many industries and there are no local producers of yeast in Canada. This research will focus on optimizing the growth of selected marine yeast strain isolated from the marine environment for […]

KASTx Ventures is a full-service biotech accelerator and advisory firm with a vision of turning today’s best science into tomorrow’s best ventures. KASTx is working with world-leading start-up biotechnology companies with a shared vision to have a positive and sustainable impact globally, focusing on the areas of health, technology, and environmental sustainability. This project will […]