Team collaboration is important for performing image-guided surgery, including laparoscopic surgery. Therefore, training healthcare providers in a team setting is critical for the success of laparoscopic procedures. To improve the quality of any team training program, we need to develop a reliable assessment instrument to measure team performance. The currently available team assessment tools are […]

Severe hemorrhage is a leading cause of mortality, accounting for upwards of 100,000 annual deaths in North America and 1.9 million worldwide. Under this condition, in a process called hemostasis, platelets in blood aggregate to form a plug to seal the blood vessel wound. During hemostasis platelets also contract to strengthen this plug, thus generating […]

Le cancer du sein triple négatif (CSTN) est un sous-type très hétérogène de cancer du sein qui présente un mauvais pronostique pour les patientes. En plus de présenter des taux élevés de chimiorésistance, l’importante hétérogénéité intra-tumorale du CSTN complique grandement le traitement des patientes. La progression tumorale est caractérisée par la régulation réciproque des reprogrammations […]

One major challenge in studying holdfast bioadhesive properties is that cells synthesize only a very small quantity of holdfast at one pole of the cell. Therefore, all studies of holdfast bioadhesive properties have been conducted by atomic force microscopy (AFM). While AFM is a powerful technique, any development of holdfast for practical applications will require […]

The proposed research project seeks to explore the application of foam-like inserts to improve the shelf life of commonly used proteins. Many commercial proteins are used in a variety of applications such as food production, pharmaceuticals, and scientific research. These proteins must be stored at sub-zero temperatures as they are prone to degradation at higher […]

Communication between cells that make up our body is essential. It is required to ensure that our body functions accurately during our lifetime. Failure for cells to send, to receive or to correctly understand signals may lead to problems such as cancer. The cellular actors responsible for such signals are called proteins. Most, if not […]

Western honey bees are economically important insects that provide essential pollination services to agriculture. It is generally acknowledged that Varroa destructor mites, since making their way from Asia to the rest of the world, have become the most serious threat to the stability of the apiculture industry. To control V. destructor, apiculturists apply miticides, but […]

L’étudiant effectuera des recherches en laboratoire pour la détection de marqueurs d’inflammation. Il utilisera la résonance plasmonique de surface pour développer des capteurs pour les protéines associées à l’inflammation.

Honeybees are considered the world’s most devoted pollinators as they provide an essential ecosystem service that is vital to the maintenance of both wild plant communities and agricultural productivity. In Canada alone, the honeybee industry is worth over 4 billion dollars annually. Over the last years, beekeepers have been faced with major colony loss due […]

This proposed project is to develop efficient sensing materials and devices that can detect trace amounts of reactive oxygen species (ROS), in particular a type of activated oxygen, namely singlet oxygen. Detection of singlet oxygen is an important but very challenging task in biological and pharmaceutical applications. The main difficulty in detecting singlet oxygen is […]

Obesity is a well-known risk factor in many diseases, including diabetes, cancer, and heart disease, in part due to abnormal blood vessel development with fat tissue. During weight gain, the volume of fat tissues can undergo drastic changes. Normally, when new tissues develop, there is a corresponding increase in blood vessel density via a process […]

Conventional molecular discovery relies on high-throughput screening strategies (HTS) to identify molecules that match a specific set of user-defined properties. Unfortunately, due to the enormous size of chemical spaces (10^60 molecules in the case of the drug-like chemical space), HTS is usually performed over pre-built chemical libraries of moderate size, often by employing computational/AI methods […]