La stagiaire développera des méthodes d’analyses de protéines liées à l’inflammation pour la détection de la réponse immunitaire suivant une infection à la COVID. Elle procédera à l’analyse d’échantillon, la production de rapports et possiblement à la rédaction d’article. Elle utilisera des techniques de résonance des plasmons de surface.

Protocells are synthetic, cell-like microcompartments designed to mimic key aspects of living cells to provide researchers with deeper insights into primitive cellular functions and behaviours. This research project is aimed to design and synthesize functional polymer coated gold nanoparticles and clusters (AuNP and AuNCs) that are capable of self-assembly into gold inorganic functional colloidosomes. The […]

Strokes and myocardial infarctions, caused by the rupture of unstable atherosclerotic plaques in the carotid and coronary arteries, are the leading causes of death world-wide. Current clinical guidelines recommend surgical removal of plaques based solely on the degree of artery stenosis. However, stenosis alone is an incomplete determinant of stroke/heart attack risk, leading to suboptimal […]

Candida auris est une nouvelle espèce de Candida découverte depuis 2009, qui s’est propagée dans six continents, causant des épidémies nosocomiales de candidoses invasives. La mortalité élevée et la transmissibilité rendent C. auris un pathogène fongique dangereux pour la santé publique. De plus, C. auris peut développer des résistances à toutes les classes d’antifongiques (azoles, […]

Cellular agriculture aims to generate more sustainable approaches to the production of agricultural products, and this nascent field requires the development of new tools to enhance controlled cell growth. In this project, we will investigate the use of insect cell biomass to produce specific phospholipids that can be used to enhance cellular growth. We will […]

Surfactants (including emulsifiers) are a group of molecules that are critical for the function of many industrial processes and commercial products. Conventional surfactants are produced from non-renewable sources (e.g., petroleum products), can persist in the environment for long periods of time, and can be toxic to various plants and animals. “Biosurfactants” are surfactants that are […]

The main goal with this research project will be to investigate the effects of strain on cardiac tissue using in-vitro studies. This proposed research will look to analyze high levels of strain in cardiac tissue using equipment that can stretch cells, which was designed and is currently being used in the physiology lab at Bern […]

Certaines protéines peuvent réguler les parcours moléculaires dans le cerveau. Ces protéines pourraient avoir un impact sur la fonction cérébrale associé aux maladies d’Alzheimer, à l’épilepsie et à la schizophrénie. Cependant, il est actuellement impossible de vérifier ces hypothèses avec les outils modernes. Pour mieux comprendre l’impact des protéines sur le cerveau et développer ainsi […]

Deux espèces de trichogrammes parasitoïdes sont présentement utilisées pour lutter contre la pyrale du maïs, soit Trichogramma ostriniae, soit T. brassicae. Ce projet vise à connaître l’effet de l’utilisation combinée de ces deux espèces. Les deux espèces possèdent des écologies différentes notamment en ce qui a trait à la diapause. Notre hypothèse de travail sera […]

To prevent diseases such as coronavirus disease 2019 (COVID-19) and Ebola virus disease vaccines are the most effective tool. For this, the promising viral vector recombinant vesicular stomatitis virus (rVSV) is applied as production platform. Using suspension HEK293 cells, rVSV-based vectors are currently only produced in batch mode. However, the establishment of perfusion cultivations at […]

Today’s society faces several challenges in implementing and enforcing environmental protection for future generations. In this respect, supplementation of petro-based chemicals by bio-based ones is of special importance to reduce the consumption of crude oil. Among such measures, chemical surfactants can be replaced by biosurfactants, e.g. rhamnolipids which are produced via fermentation from renewable resources […]

The overarching objective of this proposal is to develop and validate a new, robust and reproducible 3D culture system that supports the clonal growth of primary sources of normal and malignant human epithelial cells and that is suitable for commercialization by STEMCELL Technologies who will partner in its development. The work will systematically address 3 […]