Breath monitoring using optical microresonators

Optical sensors are revolutionizing the physiological measurements important for diagnostic purposes. For instance, we can now use optical methods to measure heart rate, blood oxygen saturation, and even blood pressure. Optical technology, in the form of optical microresonators that can trap light at a microscopic scale, can also be used to measure very small changes […]

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Passive methane oxidation biosystems design and instrumentation

Landfill emissions can continue for decades after biogas extraction systems have been turned off. The possibility of land reclamation projects, such as turning an old landfill into a park, depends of passive, low-maintenance, technologies that can cope with these emissions. The main goal of this research is to design, construct and monitor a pilot-scale passive […]

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Développement d’un outil de détection des mucines oculaires pour l’amélioration de la médication en ophtalmologie

Avec l’augmentation du nombre de personnes sur Terre et du vieillissement dans le monde, les maladies oculaires deviennent des enjeux économiques et sociétaux. De nombreuses recherches sont en cours pour développer des vecteurs de médicament mucoadhésifs pour ces maladies afin d’améliorer l’administration des médicaments dans les gouttes ophtalmiques. Cependant, chaque individu possède une composition en […]

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Collagen-based composite bioink development

The continuous world innovation in the manifacturing techniques led to the development of highly precise technologies such as 3D printing. This technique has been then further improved in such a way to print biomaterials and cells, with extreme precision. It constitute a significant innovation for tissue engineering research. Collagen, the most abundant protein of the […]

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AI-driven evaluation of clinical electroencephalographic (EEG) recordings

The proposed project is part of a large-scale collaboration between SFU’s Behavioral and Cognitive Neuroscience Institute (BCNI) and Fraser Health Authority(FHA) in the domain of AI applied to clinical electroencephalographic (EEG) scans recorded and evaluated in the process of diagnostic workup in FHA’s public hospitals (n>40’000). The key goal of the SFU/FHA collaboration is to […]

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Modulation de l’activité des réseaux de la corne dorsale de la moelle épinière par des systèmes en boucles fermées

Les réseaux neuronaux de la moelle épinière grâce à leur position à l’interface entre les structures cérébrales et la périphérie de l’organisme, jouent des rôles fondamentaux dans notre perception des informations sensorielles (réseau de la corne dorsale : proprio-, intéro- et extéroceptives) et la production de nos actes moteurs (réseau de la corne ventrale). Contrairement […]

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Remodeling of relaxin-3 contacts on somatostatin interneurons in the amygdala of a mouse inflammatory pain model: a CLEM study with array tomography

Le projet vise à élucider les mécanismes des douleurs persistantes, et leurs conséquences sur des pathologies émotionnelles associées (anxiété). Notre hypothèse est que les modifications de l’activité des aires cérébrales impliquées dans les douleurs pathologiques et l’anxiété mettent en jeu des voies nerveuses descendantes qui relient le cortex et la moelle épinière. Le projet s’intéresse […]

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Multiplexed quantitative proteomics approaches to characterize residual host cell protein impurities in biopharmaceutical processing

Many drugs, such as those made of antibodies, are produced using cells from bacteria and other organisms. Companies such as BioVectra use this approach to produce antibody drugs efficiently and cost-effectively. At the end of the production process, residue such as protein from the “host” cells (called host cell proteins, or HCPs) must be removed […]

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Optimization of Graphical User Interface for the Digital Pathology Workstation

The workflow of pathologists will soon be revolutionized with the introduction of digital pathology allowing pathologists to view tissue samples as a digital image on a computer workstation. Such a conversion from traditional microscopy will bring many benefits to the pathologist’s workflow aiming to boost significant efficiency as well as ergonomic benefits. However, much work […]

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Improving protein content in rice grains through prime editing

Protein deficiency is a major problem affecting large scale of the world’s population. Rice, the globally desired staple food, has low protein content (7-10%) in its grains. Though rice protein content is low compared to other cereals, it is highly desired due to the presence of highly nutritious and easily digestible glutelin protein. Grain Protein […]

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