Advancing Bio-materials Production Services

Bio-materials can reduce our dependence on fossil fuels, greenhouse gas emissions and facilitate a rapid transition to a bio-based leconomy. Thus, developing novel and innovative technologies and products related to bio-materials sectors is crucial. This has !resulted in extensive research into the development of biomaterials. Most research efforts have focused on materials selection, ‘fabrication, and […]

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Engineered Polymers for Nucleic Acid Therapies

Nucleic acids such as DNA and RNA offer exceptional opportunities to fight against infectious and genetic diseases. To use nucleic acids effectively in a clinical setting, one needs to use effective delivery vehicles that can deliver the nucleic acids into the diseased cells. This project will develop effective delivery systems for this purpose. The delivery […]

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Genome-wide overexpression library in Giardia spp. for drug target discovery

Giardiasis is a foodborne and waterborne disease that affects people worldwide, and it causes enteric diseases with outbreaks of diarrhea in adults and children. There are a few drugs available for treating Giardia spp. infections and they are associated with low efficacy, adverse effects, and drug resistance is spreading. Hence, there is an urgent need […]

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Benchmarking and validation of two dosimetry software packages for radiotherapy applications.

Brachytherapy dosimetry is traditionally based on the American Association for Physicists in Medicine Task Group No. 43 report, referred to as TG-43. The TG-43 dose calculation formalism describes dose delivery around a single source centrally positioned in a spherical water phantom. Patient geometry, tissue compositions, and density heterogeneities are ignored, as are foreign objects such […]

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The Next Generation Agriculture: Role of Functional Microbiome in Cannabis Breeding strategies against biotic stress

Plants including Cannabis host distinct beneficial microbial communities on and inside their tissues designated the plant microbiota from the moment that they are planted into the soil as seed. Understanding the microbial partnerships with Cannabis has the potential to affect agricultural practices by improving plant fitness and production yield of Cannabinoids. Much less is known […]

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Machine Learning for dynamic microscopic imaging

In the proposed exchange project, we plan to develop a new collaborative partnership that integrates the expertise of advanced optical imaging instrumentation (McMaster: Fang) and image sequence analysis (INRIA: Kervrann) towards new dynamic imaging technologies. Specifically, we are interested in optofluidics imaging flowcytometers for point-of-care infectious diseases diagnosis as well as high throughput protein-protein interaction […]

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Characterization of diabetic bone at the nanoscale

Diabetes mellitus, a metabolic disease affecting 422 million people worldwide, had often been associated with a loss in bone quality and strength, causing a higher fracture risk. However, thorough characterization of diabetic bone at the nanoscale has never been completed. This may indeed be relevant, as the structure and chemistry of the nanoscale components of […]

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Cow Geographies: Ecologies of Power across the World

Domesticated over 12,000 years ago, cows are currently found in every country across the globe yet very little is known about their varied histories, geographies, and lives. This despite cows’ centrality to human pursuits of agriculture, colonization, and capitalism as well as their implication in climate change. Furthermore,even as social research on cows begins to […]

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Fabrication of strong and transparent Janus wound dressings by electrospinning

Wound dressings are indispensable in medical operation as they protect the wound from contamination by foreign matter, absorb wound exudate and control the humidity of the wound to promote healing. Mitigating technology can be integrated in modern wound dressings to expedite the healing process and reduce scarring. In this proposal, we will develop an innovative […]

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Polysaccharides cell wall dynamics and wall-related resistance in the cocoa (Theobroma cacao L.) / Phytophthora megakarya interaction disease

Cocoa (Theobroma cacao) is an important economical crop cultivated in tropical countries. Cocoa black pod disease, caused by Phytophthora megakarya, an oomycete, is the most economically important threat of cacao in Cameroon. Upon infection, oomycetes pathogens develop various strategies to gain access to the nutrients and eventually causing the death of the tissue, including the […]

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Genome-wide association study (GWAS) for biological nitrogen fixation and protein content in soybean (Glycine max)

The biologically-fixed N is more efficiently converted into protein than mineral N from fertilizers. As low protein content is currently a topic of great concern in many soybean-growing areas, improvement of BNF efficiency may reach higher protein levels with lower environmental impacts. Genome-wide association studies (GWAS) have shown excellent results in the association of single-nucleotide […]

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Développement d’une plateforme moléculaire pour le dosage de mucines oculaires

Certaines pathologies, comme la maladie des yeux secs, viennent perturber la composition du film lacrymal qui protège la cornée. Plus précisément, ces pathologies ont un impact sur la composition en protéines de la dernière couche du film lacrymal. Ce débalancement peut avoir un impact sur l’efficacité des vecteurs de médicaments de l’équipe de recherche de […]

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