Deep-learning cross-modality super-resolution imaging of the cellular network in bone

Many organisms, such as bone, depend on fluid-filled network structures for cellular transport, signaling and mechanosensing. Bone is made of a network called the lacunocanalicular network (LCN), which consists of lacunae that house osteocyte cells connected together by a network of 300-nm wide canals called canaliculi. An understanding of this vast network is incredibly important […]

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Influence of redox conditions on the fate of emerging contaminants in groundwater environments

Contaminants of emerging concern (CEC) have negative impacts on human and ecosystem health as well as the potential to develop antimicrobial resistance which is projected to result in 10 million deaths annually by 2050. Some examples of CECs include antibacterial agents, artificial sweeteners, and pharmaceuticals. Recently, the presence of these CECs has been found widespread […]

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Un nouveau regard sur les protéines et le microbiote intestinal afin de mieux comprendre les bienfaits des produits laitiers sur la santé.

La composition en nutriments a été traditionnellement considérée comme un point clé pour justifier et recommander la consommation de certains aliments. En ce qui concerne les produits laitiers, les guides alimentaires de nombreux pays ont principalement insisté sur le lien calcium-lait selon lequel un nombre minimal de portions quotidiennes de lait et produits connexes devrait […]

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Decolonizing diagnostic assessments in mathematics

The overall purpose of this research is to explore the ways diagnostic assessments enable or disable growth in mathematics understanding for children most impacted by colonialism, in particular Black and Mi’kmaw children in Mi’kma’ki or what we now call Nova Scotia. This research stems from ongoing collaborative relationships in local Mi’kmaw and Black communities that […]

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ZNF768 PROTEIN HOMEOSTASIS: at the interface of controlled and uncontrolled growth

A major cause of cancer is the loss of balance between processes that promote growth and tissue repair, and signals that inhibit overgrowth. The ultimate outcome is a state where the cell/organ cannot regulate growth processes, resulting in excessive, uncontrolled growth. Our collaborators have identified a new protein that appears to play an important role […]

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Transition to Adulthood Program

Mentoring is one identified way to support young adults as they transition out of care and are faced with the many demands of adulthood. Young adults transitioning out of care have unique mentoring needs. In recognition of these distinctive needs, a specialized mentor program manual will be developed after consulting with a variety of key […]

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Beta Redundancy in Late Ordovician Communities across the Niagara Escarpment, Ontario: Implications for Modern Conservation Policy and Science Communication

Of the five mass extinction events preserved in the fossil record, the Ordovician-Silurian mass extinction (the so-called “first mass extinction”) is unique in that it had extremely limited long-term impacts. Despite eliminating over 50% of all species on Earth at the time, shallow marine communities around the globe rapidly recovered, providing scientists a unique opportunity […]

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Modeling heterologous protein production in the model diatom Phaeodactylum tricornutum

Production of protein in different organisms has attracted interest since the first biotechnological production of insulin. Efforts had been made throughout the years to study several organisms like bacteria and yeast to produce exogenous proteins with commercial interest. During the last decades microalgae have attracted the attention as platform of production of complex proteins. For […]

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Use of algal bioassay to track water quality impairment for community-based monitoring programs in the Township of Georgian Bay

Good water quality is essential to the lifestyle, economy, and ecosystem health of Georgian Bay (GB). Unfortunately, water quality is being degraded due to an excess of nutrients entering the water through recreational development. Excess nutrients, specifically phosphorus, can lead to agal blooms, reduced water clarity, depleted oxygen levels and aquatic dead zones where wildlife […]

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Adiposité et santé cardio-métabolique et neurocognitive

Les désordres cardiométaboliques (ex. dyslipidémie, stéatose hépatique, résistance à l’insuline, diabète, etc.) et neurocognitifs (ex. troubles cognitifs, déficit de l’attention, atteinte des fonctions exécutives, démences, etc.) associés à l’obésité se manifestent différemment selon les régions du monde et selon les groupes ethniques. Certains groupes ethniques incluant les communautés autochtones et sud-asiatiques sont particulièrement affectés par […]

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Fibronectin Type III domain-containing (FNDC) : facteurs clés dans les fonctions ovariennes chez la vache ?

La vache laitière est infertile pendant les premières 10 semaines après la mise-bas, ce qui est dû en partie à une sécrétion altérée des hormones libérées par le tissu adipeux et musculaire. Une famille de telles hormones s’appelle les ‘Fibronectin domain containing’, et pendant mon projet j’ai découvert que deux de ces hormones inhibent la […]

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