Molecular Profiling of Survivin in Different Human Cancers

Survivin, a member of the inhibitors of the apoptosis protein family, is involved in multiple critical pathways of cancer cell growth and survival. Because of its selective expression in cancer cells but not in normal adult tissues, survivin is an attractive target for different cancer treatments. Immunovaccine Inc. (IMV) has developed a therapeutic cancer vaccine, […]

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The impact of social distancing on biological rhythms and mental health: a study of the effectiveness of interventions in biological rhythms and sleep

Under the conditions of social distancing during the COVID-19 pandemic, most individuals are experiencing a major shift in daily routines. For some, having a flexible work schedule may be beneficial to their natural bodily rhythms. For others, the lack of structure that was previously provided by an external schedule may impose misalignment on behavioural circadian […]

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AI-based Platform for Population-level Social Isolation Detection and Prediction

Social isolation is a serious public health issue which has many negative effects on quality of life and well-being of individuals. This research project aims to develop and test a Minimally Viable technology platform (MVP) to tackle population-level social isolation. This platform is designed to collect and analyze surveys from the users and detect socially […]

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Fundamental movement skills in children with physical disabilities

In Canada, 4.2% of children under the age of 15 years are living with physical disabilities. For children with physical disabilities, participation in physical activity is limited. A common factor attributed to reduced physical activity is physical literacy, defined as a multifaceted conceptualization of the abilities required to be engaged in physical activities for life. […]

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Health’s Wayward Sisters: An Examination of Diet, Disease, and Mortality Using a Syndemic Perspective

My proposed Mitacs-funded research will study health and disease in the medieval (11th-15th centuries AD) population from St. Peter’s Monastery in Osor, Croatia through a study of disease patterns, biochemical analysis of diet, and mortality trends. I will use syndemic theory to frame my research, which maintains that diseases and health conditions can interact with […]

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Fabrication of strong and transparent Janus wound dressings by electrospinning

Wound dressings are indispensable in medical operation as they protect the wound from contamination by foreign matter, absorb wound exudate and control the humidity of the wound to promote healing. Mitigating technology can be integrated in modern wound dressings to expedite the healing process and reduce scarring. In this proposal, we will develop an innovative […]

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Development of a Sustainable Program Quality Improvement Framework using a Balanced Scorecard Methodology at Family Services Ottawa

FSO (Family Services Ottawa) is a not-for-profit social service agency whose mission is to assist individuals, to build on their strengths and to improve their mental health. FSO does so by providing counselling, education, and advocacy within a context of working to foster systemic change. Although their programs are increasingly monitored and evaluated at the […]

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Real-time Analytics and Decision Support for Patient Flow Management 2

Large community hospitals and teaching hospitals in Ontario operate at congestion levels most of the time. This translates into long wait times for the patients, cancelled procedures, undue stress for the clinical staff, and inefficiency in hospital operations. In order to address the bottlenecks in patient flows, decisions are made by the clinical staff based […]

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AI-Powered Dispute Settlement

The objective of this project is to develop an algorithmic system, trained on both public legal data and proprietary negotiation data, that will provide tailored predictions of likely court-based dispute resolution outcomes and optimal settlements. In the proposed sub-project, a team of interns (JD students) will be modelling and labelling dispute-resolution data on complaints against […]

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Identification de signatures mutationnelles liées aux stress réplicatif

Les cellules humaines vont toutes subir des dommages à l’ADN durant leur vie. Ces dommages peuvent être causé par des facteurs environnementaux ou biologiques, mais la majorité du temps ces lésions vont être réparées par une des multiples voies de réparation de l’ADN de la cellule. Quand le dommage n’est pas réparé ou s’il est […]

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Worker Cooperatives, Newcomer Youth and Economic Mobilities

We are interested to explore the value and impact of worker co-ops as a vehicle for migrant youth to build skills and experience, and enable economic mobilities. Solid State has found considerable success working with newcomer youth in Surrey, BC. Through this project, we are interested in understanding how this work might travel from coast […]

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