Expanding the Applicability of Inductively Coupled Plasma Tandem Mass Spectrometry in Clinical and Semiconductor Industries

This internship aims at advancing the use of inductively coupled plasma (ICP) tandem mass spectrometry (MS/MS) for the analysis of clinical samples (including whole blood) and of materials used by the semiconductor industry during their manufacturing process. The complexity of biological samples indeed limits the broad use of conventional inductively coupled plasma mass spectrometry (ICPMS) […]

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Internet-based mental state monitoring using patient’s textual data

Among all chronic diseases, mental health issues have the highest burden on health care systems. However, unlike other chronic diseases, like Diabetes or hypertension, no monitoring procedures exist to monitor patients’ mental health status to prevent relapse and crisis situations. It is therefore necessary to develop cheap, convenient and accessible monitoring systems that could be […]

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Internet-based mental state monitoring using patient’s textual data – Year two

Among all chronic diseases, mental health issues have the highest burden on health care systems. However, unlike other chronic diseases, like Diabetes or hypertension, no monitoring procedures exist to monitor patients’ mental health status to prevent relapse and crisis situations. It is therefore necessary to develop cheap, convenient and accessible monitoring systems that could be […]

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AccessiBelt – Car Seatbelt for Users with Limited Hand Dexterity

Our hand function can be affected by different diseases and disorders, such as arthritis and neurological injuries. Having limited hand function will immensely affect our life and will make everyday simple tasks challenging. There are about 1 million Canadians who reported struggling with daily activities due to this limitation. One task that is challenging for […]

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Automated Multi-Factor Medium Optimization of Human Hematopoietic Stem Cell Expansion Using Design of Experiments

This project aims to support ExCellThera’s current clinical trial (ECT-001) to improve blood stem cell transplantation outcomes for patients suffering from a host of blood malignancies. A critical aspect of developing clinical therapies using stem cells involves accurate and robust control of stem cell behavior in controlled laboratory conditions. Cell growth conditions (media) should mimic […]

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Resistant Starch Prebiotic Effects in Chronic Kidney Disease (ReSPECKD) study

Chronic Kidney Disease (CKD) is associated with a reduced quality of life and an increased risk of kidney failure, cardiovascular events, and all-cause mortality. The goal of this project is to investigate whether the consumption of resistant potato starch (RPS) in addition to current standard care for CKD will reduce uremic toxins and symptoms by […]

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A Novel Cognitive Remediation Intervention for Public Safety Personnel with Post-Traumatic Stress Disorder (PTSD)

Urgent calls exist to address the mounting crisis of mental illness, and in particular posttraumatic stress disorder (PTSD), among public safety personnel (PSP; e.g., firefighters, police, paramedics) in Canada. Critically, PTSD is associated with alterations in cognitive functioning (e.g., poor memory and attention) that disrupt the ability of PSP to engage in activities such as […]

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A Novel Cognitive Remediation Intervention for Public Safety Personnel with Post-Traumatic Stress Disorder (PTSD) – Year two

Urgent calls exist to address the mounting crisis of mental illness, and in particular posttraumatic stress disorder (PTSD), among public safety personnel (PSP; e.g., firefighters, police, paramedics) in Canada. Critically, PTSD is associated with alterations in cognitive functioning (e.g., poor memory and attention) that disrupt the ability of PSP to engage in activities such as […]

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Development, implementation and validation of new anti-E6 therapeutics for the treatment of HPV-associated cancer

Human papillomaviruses (HPVs) are responsible for almost all cervical cancers. Current treatment available relies on chemo- or radiation-therapy or surgery. These methods have several side-effects with high morbidity and survival of just ~ 70%. Our lab, therefore, develops a more patient-centered approach based on targeting the viral E6 protein, the main culprit of carcinogenesis in […]

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Development, implementation and validation of new anti-E6 therapeutics for the treatment of HPV-associated cancer – Year two

Human papillomaviruses (HPVs) are responsible for almost all cervical cancers. Current treatment available relies on chemo- or radiation-therapy or surgery. These methods have several side-effects with high morbidity and survival of just ~ 70%. Our lab, therefore, develops a more patient-centered approach based on targeting the viral E6 protein, the main culprit of carcinogenesis in […]

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Application of MagLev-based isolation technology for rapid and sensitive detection of Influenza virus

Influenza is a viral pathogen responsible for annually claiming thousands of lives (~650 000 per year) and posing a significant threat to all human life. In Canada, Influenza pandemics lead to direct economic losses including medical costs (estimated mean cost per treatment: $14,612.00), and indirect losses such as substantial workplace absence (Avg 10.8 days). Additionally, […]

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