Improving cancer care operations

This project is composed of three sub-projects, all sharing the goal of improving cancer care operations. The first project aims to improve the scheduling of ambulatory clinics at Princess Margaret Hospital and Women’s College Hospital. Better scheduling will result in less overtime, improved utilization of shared resources, and increased patient satisfaction. The second project is […]

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Fibre in IBD: Feeding Our Microbes vs. Fuelling Inflammation – Year two

While studies show that dietary fibres are beneficial in many diseases, they are not digested or absorbed directly by the host, but rather fermented by gut microbes. Fermentation byproducts (mostly short-chain fatty-acids; SCFAs) are responsible for health benefits. Only select inflammatory bowel diseases (IBD) patients benefit from fibres; many patients report sensitivity to high fibre […]

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Mimicking Lung- and Gut-Pathogen Interactions Using a Hydrogel-Based Mucus Layer

The objective of this research is to investigate long-term interaction between host cell and pathogen. Research will be proceed using ATPS(Aqueous two phase system) and hydrogel. ATPS enable pathogen to form localized biofilm on mammalian cell tissue. To see long-term interaction, biofilm will be stably localized on mammalian cell using hydrogel, which protect mammalian cell […]

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Caractérisation de la viabilité et de la fonction des granulocytes destinés à la transfusion

Les granulocytes sont une première ligne de défense très efficace contre les infections. Lorsqu’ils sont en nombre insuffisant ou qu’ils se dérèglent, de graves infections peuvent survenir. La transfusion de granulocytes est alors toute indiquée pour les patients aux prises avec une infection sévère résistante aux traitements habituels. Toutefois, nous ne savons pas si ces […]

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Evaluation of Resiliency in Community Youth Empowerment Programs

Youths experience increased vulnerability to mental health challenges associated with their development and living contexts. Effective mental health promotion must consider the multidimensional determinants of resilience. To address these needs, Dr. Jenny Liu (Elevate applicant) has developed and validated an innovative model, Multi-System Model of Resilience (MSMR), which measures resilience capacities and needs at the […]

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Evaluation of Resiliency in Community Youth Empowerment Programs – Year two

Youths experience increased vulnerability to mental health challenges associated with their development and living contexts. Effective mental health promotion must consider the multidimensional determinants of resilience. To address these needs, Dr. Jenny Liu (Elevate applicant) has developed and validated an innovative model, Multi-System Model of Resilience (MSMR), which measures resilience capacities and needs at the […]

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Identification of beneficial probiotics for non-alcoholic fatty liver disease and elucidation of mechanism

Non-alcoholic fatty liver diseases (NAFLD) is cause by accumulation of lipid droplets in liver. NAFLD is the starting point of liver disease and later develop into nonalcoholic steatohepatitis, cirrhosis and finally hepatocellular carcinoma. Since there is no specific therapeutics for NAFLD-related liver diseases, development of new drug for NAFLD/NASH is actively on-going. Recently, application of […]

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Enhancing exercise adherence in people with persistent musculoskeletal pain using a behaviour change approach

Persistent pain is pain that is prolonged beyond normal healing time, usually defined as three months. Approximately one in five Canadians suffer from persistent pain conditions such as low back pain, osteoarthritis and fibromyalgia. These conditions account for $43-60 billion in healthcare costs. Prescribed exercise has been shown to decrease pain while increasing function and […]

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Impact of parental cognitive sensitivity on at-risk children’s empathy development

The objective of this study is to explore how cognitively sensitive parenting fosters the development of children’s empathy in at-risk children. To date, there is some research that suggests that the parent-child relationship contributes to the development of empathy in children. Parents who exhibit cognitive sensitivity promote mutual and positive interactions, adjust their behaviour according […]

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Development of fast photocrosslinking bioinks for visible light-based stereolithography 3D bioprinting

The research projects aims to develop the fast photocrosslinking bioinks for visible light-based stereolithography 3D bioprinting. In order to prepare bioinks for 3D bioprinting, alginate was modified with tyramine which is phenol group and gelatin was modified with glycidyl methacrylate. Compound with alginate-tyramine derivatives(Alg/Tyr) and gelatin-methacrylate(GelMA) will improve its 3D printability, mechanical properties and cell […]

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Succeed and Stay

The Greater Saint John area struggles. Too many people are leaving, not enough people are moving in. If this continues, governments will have great trouble. It will be hard to pay for road repairs, keeping schools open and so on. Likewise, employers already struggle to find people for the positions that do open up. Locals […]

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