Developing a DARTS proteomics method to identify the host-based targets of KSHV lytic replication inhibitors

Kaposi sarcoma-associated herpesvirus (KSHV) is virus, whose unabated lifecycle results in the formation of cancerous tumorous. Moreover, KSHV infection is particularly prevalent in people living with HIV, and has a disproportionate burden in sub-Saharan Africa. Despite this clear unmet medical need, there are no approved treatments for KSHV. Recent work, conducted in South Africa has […]

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Building AbilityGPT – A GPT model to create novel biological therapeutics

Antibody therapeutics are a fast-growing class of treatments for many significant unmet medical needs. Ability biologics is a Montréal-based startup company that has significant unique proprietary data, sequences and activities for over 40 targets, for training deep-learning models, combined with laboratory facilities to create and test antibodies proposed by computer models. Ability Biologics will use […]

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Exploring the automation of animal health surveillance through natural language processing: A comparative analysis of supervised and unsupervised approaches for canine gastroenteritis

Canine gastroenteritis is a syndrome characterized by inflammation of the stomach and intestines, resulting in acute onset diarrhea, vomiting, and anorexia. As no prophylactic treatment exists, veterinary health preparedness based on surveillance is a key preventive strategy. We propose a comparative empirical study applying various language modeling approaches to identify gastroenteritis outbreaks in UK dogs […]

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Developing ethical training for long-term care through narrative

The project will recruit and interview staff at a number of long-term care (LTC) facilities about their experience of making difficult, ethical decisions. Materials from these interviews will be used to write a number of case studies, which participants will then discuss in focus groups. All interviews and focus groups will be recorded and transcribed. […]

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Community Engaged Architecture

The research project aims to investigate how racialized communities relationship with public space can be improved with community-engaged architecture. The intern will use a post-occupancy evaluation to understand the impacts of the community-engaged designed public space, 1700SPOT, for the residents of Russell Heights. Impact is evaluated with consideration to racial and gender equity.

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A Point-of-Care Test for Tick-Borne Diseases

Lyme disease is a tick-borne infection caused by the bacteria Borrelia burgdorferi. It requires early detection for effective antibiotic treatment. Unfortunately, Lyme disease is hard to diagnose, and current tests require trained scientists, specialized lab settings, and expensive equipment. Here, the project aims to develop a quick, low-cost, and user-friendly test for Lyme disease that […]

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The Effects of Sex Differences on Acute Muscle Protein Synthesis Responses following High-Intensity Interval Training

Musculoskeletal conditions, such as sarcopenia and frailty, have been documented to affect over one billion individuals globally. To address the escalating issues of muscle atrophy, resistance training (RE) has been widely recognized for preserving and enhancing muscle mass. However, individuals nowadays often face time constraints, making it challenging to consistently engage in RE. Considering this, […]

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Improving health and healthcare for adults with neurodevelopmental disabilities

CAMH is Canada’s largest mental health hospital and is also one of the world’s leading research centres in the field of mental health. The organization conducts groundbreaking research, provides training to health care professionals and scientists, develops health promotion and prevention strategies, and advocates for public policy change. More specifically, the Azrieli Adult Neurodevelopmental Centre, […]

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Remote Patient Blood Glucose Monitoring using rPPG

The project will enable contactless measurement of blood glucose using remote Photoplethysmography (rPPG) technology using patients’ face or finger videos which is a comparatively new artefact. There is a lack of training data and the blood volume pulse (BVP) signal extracted from the videos suffer from a lot of noise resulting in poor measurement accuracy. […]

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Application of engineering grade vector flow ultrasound in human physiological study

This project will stimulate discovery into blood flow dynamics and strengthen ties between Canada and Japan. By learning advanced techniques from Japan’s cutting-edge Verasonics ultrasound system, the intern will study large veins and the heart during physiological stressors including body tilting, breathing maneuvers and exercise. The potential discoveries may help uncover diagnostic imaging capabilities to […]

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