En recherche sur le cerveau, l’imagerie et la stimulation cérébrale sur le modèle animal sont des techniques de référence. Dans ces expériences, l’expérimentateur doit manipuler l’animal (la souris le plus souvent), ce qui réduit la qualité de données qui peuvent être collectées. Afin de dépasser cette limitation, une nouvelle stratégie d’acquisition basée sur des cages […]

Dans le cadre d’une restructuration, Orica souhaite réhabiliter une partie de son site localisé à Brownsburg-Chatham au Québec. Le site qui accueille depuis 1870 une usine de production d’explosif est non seulement contaminé, mais présente des risques importants pour les écosystèmes et la santé humaine. Ainsi, l’entreprise souhaite développer une approche verte qui vise à […]

We propose to develop in collaboration with Medtronic Canada a bioceramic drug delivery system for the local controlled release of Biphosphonates (BP) – drugs that prevent bone resorption – to promote both tumor inhibition and bone regeneration at the site of bone tumor resection, eliminating the need for high systemic doses and side effects associated […]

This project aims to determine and suggest how often equipment inspections should be conducted to minimize equipment downtime. A calculation will be made to determine the optimal amount of inventory and spare parts for equipment maintenance under the shadow of preventive maintenance. This project also involves determining the duration and probability of maintenance and inspections. […]

The use of business process modeling (BPM) and analytics has demonstrated exceptional results in improving efficiency and effectiveness in various industries. Health care processes however, are characterized by uncertain, exception and continual evolution. This project aims to apply flexible, adaptive and evolutionary process modeling protocols coupled with operations research and other analytic methods to the […]

The long-term effects of COVID-19 on individual health remain to be elucidated, with numerous reports emerging of fibrotic changes in the lung beyond the acute phase of the disease. Considering the reported cases of COVID-19 worldwide, even a small percentage of these patients developing lung fibrosis can have detrimental consequences on our healthcare system. In […]

This research presents a new experimentally tuned reduced-order modeling methodology employing a hybrid stick model representation. Digital image correlation (DIC) is used to synthesize mode shapes within a frequency range of interest during Ground Vibration Testing (GVT). Experimental mode shapes are augmented into the Guyan Reduced Order Model (ROM) to develop a corresponding Craig-Bampton ROM. […]

The blown plastic film industry is constantly evolving, and the simpler products of just a few years ago are being displaced by new technical films. Market pressures have demanded a lower cost of plastic film with higher quality and thinner gauges. As a result of these trends, the demand for improvements in gauge control of […]

AV Nackawic is part of a new and innovative group of companies (AV Group), which are focused on producing specialty pulp products to service the textile and paper industry. The pulp produced is the raw material for the rayon production process, where reactivity of pulp is an important parameter determining the quality of the product. […]

Recently, a new foot orthotic design which adds texture between the skin at the bottom of feet and the top of an orthotic has gained academic attention. Adding this texture is intentional to activate the receptors in foot sole skin, to send this added stimulus into the spinal cord, and target changes in muscle activity […]

The use of aluminum alloys in automotive applications is increasing since this allows the weight of the vehicle to be decreased. This is beneficial for both internal combustion and battery powered vehicles, to increase fuel economy and increase vehicle range, respectively. However, in general, aluminum alloys are more difficult to form than steel and their […]

The major aim of this research project is to accelerate the development of the SORT1+ oncology platform. This novel platform is based on a new proprietary peptide targeting Sortilin, a key scavenging receptor. Sortilin has been reported to play a role in cell survival and in the progression of human cancers. For instance, Sortilin expression […]