Chemotherapy drugs target and kill rapidly-dividing cells located closest to blood vessels, but do not penetrate deep into the tumor. Limited drug distribution in tumors is an important cause of drug resistance. A method to increase tumor drug delivery and combat resistance is the subject of this proposal. To counteract chemotherapy resistance, the use of […]

Increased energy consumption across the world for heating and cooling indoor living spaces has been a major contributor to global greenhouse gas production. As per 2015 statistics, buildings account for 76% of global electricity consumption and approx. 35% of that energy consumption is for air conditioning, heating, and ventilation. To combat climate change it is […]

ViroCarb has identified a new class of HIV inhibitors against a new therapeutic target on the HIV envelopeprotein gp120, present in all HIV, including drug resistant strains. The objective of this internship is to conduct screening studies of libraries, designed based on this new chemical class for optimal efficacy and drug-like properties, using methods previously […]

Corrosion is the destructive attack of a metal by a chemical or electrochemical reaction with its environment. Corrosion of industrial and mechanical infrastructure causes severe economic losses. Canadian corrosion-related expenses amount to $41 Billion CAD annually. The extensive oil and gas pipeline networks in Canada require approx. $1 Billion CAD annually for replacement and/or maintenance. […]

La compétition entre les arbres pour les ressources du milieu s’intensifie à mesure que la forêt se développe. Le traitement sylvicole alors utilisé afin de réduire la compétition est l’éclaircie précommerciale (EPC), qui vise la libération et la redirection des ressources vers les essences d’arbre désirées. Dans la forêt boréale, le couvert végétal au sol […]

Developing an efficient process for MSW pyrolysis is important to reduce the environmental and spatial impact of MSW in landfills. This project aims to evaluate the production of renewable fuels from MSW using a dual spinning disc reactor (DSDR). The DSDR, developed by Vorsana, has the flexibility to handle several pyrolysis feedstocks under controlled conditions […]

Development of an Avionics system test methodology, based on the Test and Test Control Notation (TTCN-3). This will include (1) a gap analysis between TTCN-3 and current avionics test languages and environments and (2) a large scale case study. Of particular interest, will be the ability to model and verify both continuous control and discrete […]

York University and Jazz Pharmaceuticals are undertaking a project to accelerate development of their Leukemia drug candidate. The project will take advantage of unique technologies developed at York by Drs. Wilson and Krylov, Millisecond Hydrogen Deuterium eXchange (msHDX) mass spectrometry and Kinetic Capillary Electrophoresis (KCE), to provide a high-detail picture of Jazz Pharmaceutical’s candidate, including […]

High-level control strategies, commonly referred to as Motion Cueing Algorithms (MCA), are used to create realistic perception of unrestricted 6 degrees-of-freedom (DoF) motion with a motion platform that has fewer DoF and a limited workspace. For instance, such an algorithm would tilt the platform towards back to emulate forward acceleration on a platform that does […]

L’émergence des produits cosméceutiques représentent le segment dont la croissance est la plus rapide au cours des dernières années dans le marché des cosmétiques. Ces produits reposent sur le choix des ingrédients actifs. Parmi ces derniers, les actifs marins ou issus et biotechnologies marines sont de plus en plus recherchés. En effet, les algues et […]

This project aims to develop an strong e-commerce strategy for a Toronto-based biomedical start up, Shiphrah Biomedical Inc.. Shiprah Biomedical Inc. is tackling one of the biggest challenges in pregnancy: sleep, and one of the biggest challenges in sleep: pregnancy. Through this project, Shiphrah Biomedical Inc. will be able to get their flagship product to […]

La demande en beurre est en forte croissance au Canada ce qui nécessite de maximiser sa production. Toutefois, les différentes étapes de production de la crème en usine peuvent avoir un grand impact sur la texture du beurre. Il est donc primordial de développer des outils d’évaluation des crèmes afin de pouvoir proposer des stratégies […]