Development of a biosensor for high-throughput screening of novel ezrin inhibitors for treatment of metastatic breast cancer.

Treatment of metastatic breast cancer is often unsuccessful and lead to 5000 deaths in Canada each year. Therefore, there is an unmet need for new drugs for prevention and/or treatment of metastatic disease. Ezrin is a protein marker commonly over-expressed in metastatic breast cancer. Preclinical studies show that blocking ezrin can significantly reduce metastasis in […]

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Examination of beneficial effects of copper fabric on cardiometabolic status, and mechanistic role of gut microbiome

Copper has long been proposed to have important biological properties. Designed to deliver the health benefits of copper, CuTEC yarn is a USPTO|EPO patent pending, bio-engineered copper-based yarn that can be produced as products such as clothing and mattress ticking. Although many believe in the positive properties of copper for well-being, many remain retiscent to […]

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The Generation of Market and Ethical Values in a Canadian Wild Food Network

This research focuses on a product of growing popular interest: “wild foods” like morel mushrooms, wild blueberries and fiddleheads. Why do the people who produce, trade and consume these foods value them? How can this value, whether economic, social or ecological, be increased? Because the attraction of these foods comes from their being “wild,” and […]

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Measurement of the physical and thermo-physical properties of molten salts and their interactions with materials of construction

Small Modular Reactors (SMRs) represent the next generation in nuclear power reactor technology with the benefits of being non-greenhouse-gas emitting forms of power production and providing inherent safety, lower construction and operating costs and proliferation resistance. As part of the recently announced New Brunswick SMR Research and Development Cluster, Moltex Energy proposes to build their […]

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Caracterisation du comportement electrique et thermique de structuresde materiaux composites de carbone dans Ie cadre de la recherche de solutions deretour de courant

Le projet vise a ameliorer la connaissance des proprh§tes electriques et thermiques des materiaux composites dans Ie contexte de leur utilisation dans Ie milieu aeronautique. Pour ce faire, il est envisage de soumet!re des echantillons de ces materiaux a des courants electriques, pour en evaluer la distribution dans lesdits echantillons. L’echauffement cause par ces courants […]

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Safety Labs User and Performance Validation

The Safety Labs platform is an ‘always connected’ Internet of Things (IOT) cloud computing based system that focused on aging in place and well being for older adults through ongoing health knowledge. This project will focus on a trial with a population of older adults in the Ottawa region that will trial the system with […]

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AI Nétur

This project deals with the development of three applications of Artificial Intelligence and Operations Research aiming at improving the cost, response time and flexibility of production cost assessment, process planning and production at Nétur. Nétur manufactures high precision parts for Original Equipment Manufacturers (OEM) in the aerospace industry, such as Pratt & Whitney. Data mining […]

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The inhibitory effect of Aevo Oral Ultrasound Gel on dental bacteria

Dental caries affects the majority of the world’s population and causes tooth decay and loss. Bacteria in the mouth cause this disease. Sugar consumption plays a role in causing these bacteria to make acid that results in dental caries. Studies have shown that a type of sugar alcohol, called xylitol, can help prevent this disease. […]

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Tool Development for Bolus Shaping in Radiation Therapy

During External-Beam Radiotherapy in cancer therapy, Bolus, a thick sheet of flexible material, is used to cover the skin surface in order to minimize damage healthy tissues. A significant problem of using bolus is air gaps generated between the bolus and patient’s skin if an inaccurate shape of bolus was made. In this research, an […]

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Multiphysics modeling of novel electrical powertrain for medium-duty trucks

Electric motors for traction applications come in many types, but in-hub induction motor with concentrated winding is not one of them. This specific configuration is of high interest for Nordresa – an electric truck manufacturer based in Montréal, Canada. In effect, this motor type presents numerous advantages: because of the concentrated winding and the absence […]

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Techniques for Mapping, Analyzing and Improving Complex MultifunctionalProduct Development Processes

Existing methods and techniques for process mapping will be considered to develop a process framework which will be adapted to perform analysis and provide improvements to the process. Analysis techniques will be applied to detect redundant, duplicated or misaligned process activities. Results will provide means to assess and evaluate the discrepancies between the actual and […]

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