With an average median survival of 14 months, glioblastoma multiforme (GBM), the most common and most aggressive primary brain tumor occurring in adults, represents an unmet medical need and new therapeutic options with a significant impact on patients survival are eagerly awaited. Our laboratory recently identified the enzyme CD73 as a new target for cancer […]

With an average median survival of 14 months, glioblastoma multiforme (GBM), the most common and most aggressive primary brain tumor occurring in adults, represents an unmet medical need and new therapeutic options with a significant impact on patients survival are eagerly awaited. Our laboratory recently identified the enzyme CD73 as a new target for cancer […]

Recent discoveries show that neutrophils mainly die by formation of neutrophil extracellular traps (NETs) in Cystic Fibrosis airways. Therefore determining mechanism and identifying FDA-approved drugs that inhibit NETosis could provide novel options to treat CF lung disease. We aimed to do the comparative gene expression analysis during NETosis induced by different NET inducing agents (PMA,LPS,A23187) […]

Recent discoveries show that neutrophils mainly die by formation of neutrophil extracellular traps (NETs) in Cystic Fibrosis airways. Therefore determining mechanism and identifying FDA-approved drugs that inhibit NETosis could provide novel options to treat CF lung disease. We aimed to do the comparative gene expression analysis during NETosis induced by different NET inducing agents (PMA,LPS,A23187) […]

Youth are tomorrow’s leaders, parents, professionals, and workers, as well as today’s assets. However, the disengagement and out-migration of rural youth are critical challenges for rural communities and regions. In the Lower Columbia and surrounding West Kootenay-Boundary region these challenges are compounded by struggles to meet existing labour force needs. This project will review, summarize, […]

Parents suffering from toxic stress (depression, addictions, and/or family violence) are often unable to respond sensitively and appropriately to their infants, putting the health and development of their infants at risk. My research evaluates a new parenting program called ATTACH. In ATTACH, parents learn to reflect on how they parent and to better understand their […]

On the coast of British Columbia, both eelgrass meadows and Pacific salmon species are declining, yet eelgrass community dynamics and reliance of juvenile salmon on these communities are poorly understood. We will assemble the first large-scale dataset from monitoring efforts of coastal BC organizations in order to assess eelgrass community diversity and structure across environmental […]

On the coast of British Columbia, both eelgrass meadows and Pacific salmon species are declining, yet eelgrass community dynamics and reliance of juvenile salmon on these communities are poorly understood. We will assemble the first large-scale dataset from monitoring efforts of coastal BC organizations in order to assess eelgrass community diversity and structure across environmental […]

Without careful management, the growing number and intensity of human activities can negatively affect ecosystem health and cause conflict between users. Recognizing the need for integrated management, the Province of British Columbia and 18 Coastal First Nations collaborated to develop an integrated spatial Marine Plan for the North Pacific Coast. A critical part of implementing […]

Soft tissue sarcoma is a disease that affects patients of all ages and have profound societal impact. On average 17 life years per patients are lost due to sarcoma, which is 2-3 times more than bowel, lung, prostate or breast cancer. Patients with soft-tissue sarcoma represents one the top 5 most important cancer cause of […]

It is estimated that 1 in 2/3 people will be diagnosed with cancer in their lifetime. Cancer is a genetic disease characterized by the uncontrolled growth of cells. While treatments are available for many cancers, remission of the disease, side-effects of the medication, and the onset of resistance by the cancer to the drugs being […]

DeepCity is a strategy game initially for iOS, Android and desktop that is set in a strange, fascinating near future of mega-storms and scarcity. The goal: Survive. Defend. Regenerate. DeepCity advances concepts of resilience, urban ecology, sustainable futures, and systems-thinking within urban environments for players. The DeepCity prototype research project will provide the student with […]