Gene therapy is one of the most attractive new therapeutic strategies in the treatment of multiple diseases. However, to apply gene therapy in clinic, an efficient and safe delivery system must be developed to transport these therapeutic reagents to target organs. The existing gene carriers suffer from either high cytotoxicity or immunogenicity problems, which will […]

Post-traumatic stress disorder (PTSD) emerges after the exposure to an event that elicits horror or helplessness, including threat of injury or death to one’s self or another person. Community-based studies have evaluated its occurrence with a lifetime prevalence of 9.2% in the Canadian population. This research project aims to develop innovative, neural-substrate based, and novel […]

Future broadband cellular systems will require very high throughput data transmission to satisfy ever increasing demands of mobile users for high speed multimedia services. Using innovative approaches to multiantenna transmission/reception and to cooperation of network nodes the achievable data rates can be greatly increased. Two significant obstacles to achieving very high data rates are interference […]

Non-small cell lung cancer is the leading cause of cancer deaths worldwide. Resistance to treatments results in a very poor long-term prognosis. VAL-083 is a chemotherapeutic drug that has activity against lung cancer in cell-studies and in clinical trials. It may be an effective treatment option for drug-resistant lung cancer. However, the detailed mechanism of […]

Antibodies are the fastest growing segment of the pharmaceutical market, and with modern engineering technologies antibodies can be programmed to target devastating diseases. Within the immune system, antibodies fight invading bacteria and viruses. High-quality synthetic antibodies directed to disease-related targets have immense therapeutic potential. Development of cell-based assays to enable rapid identification of functionally active […]

The goal of this project is to develop the first ever high definition integrated water circulation and water quality model for the Toronto Waterfront. As one of the most urbanized freshwater ecosystems with complex geometries and physical processes, Toronto Waterfront is in an urgent need for modern scientific tools that can support effective environmental management […]

Ericsson Ottawa develops cellular base stations that are components of cellular networks marketed by Ericsson. The base stations serve as the interfaces between mobile devices (cell phones) to wired networks and the internet. These network products require high reliability and availability, which results in the need to perform extensive testing on expensive hardware, replicating complex […]

The research project will develop key algorithms that enable pulse oximetry, on a smartphone, to be used effectively as a sleep apnea screening tool. LGTmedical has developed pulse oximetry that utilizes inexpensive clinical sensors driven by software running on a smartphone, sending the driving signals through the audio port. This technology already operates with clinical […]

The continuously increasing demand for wireless access, driven by the increasing requirements of our connected society, is pushing current wireless cellular communication systems to the limits of their capacity. The objective of this project is to continue the successful collaboration with our industry partner (Telus Corporation) to further contribute to the evolution of current generation […]

The continuously increasing demand for wireless access, driven by the increasing requirements of our connected society, is pushing current wireless cellular communication systems to the limits of their capacity. The objective of this project is to continue the successful collaboration with our industry partner (Telus Corporation) to further contribute to the evolution of current generation […]

On the coast of British Columbia, both eelgrass meadows and Pacific salmon species are declining, yet eelgrass community dynamics and reliance of juvenile salmon on these communities are poorly understood. We will assemble the first large-scale dataset from monitoring efforts of coastal BC organizations in order to assess eelgrass community diversity and structure across environmental […]

On the coast of British Columbia, both eelgrass meadows and Pacific salmon species are declining, yet eelgrass community dynamics and reliance of juvenile salmon on these communities are poorly understood. We will assemble the first large-scale dataset from monitoring efforts of coastal BC organizations in order to assess eelgrass community diversity and structure across environmental […]