Development of an automated system for counting fetal and maternal red blood cells in clinical KB Test

The Kleihauer-Betke (KB) test is the standard method for quantitating fetal-maternal hemorrhage in maternal care. The critical component of the KB test is the counting of fetal and maternal red blood cells (RBC). However, manual counting still the dominant clinical method for KB test. Manual RBC counting takes ~20 minutes. In a standard procedure, a lab technologist, looking through the eyepieces of a microscope, manually counts about 2,000 RBC and calculates the fetal-maternal RBC ratio.

Thermal Analysis of Poly-V Belt Transmission System

Nowadays, automotive companies are seeking to use prospective robust, light-weight, anti-corrosive and cost-effective composites such as fibre reinforced polymer (FRP), instead of traditional materials like steel or aluminum alloy, to make their products more competitive in the market. The sponsor company in this project, Litens Automotive Group, is investigating the feasibility of adopting FRP to manufacture high torque capacity drive pulleys.

Nonlinear Dynamic Analysis of Aero-Engines

Aero-engines are lightweight structures which are assembled of several thin walled cylindrical components (casings). Casings are joined by bolted flanges, and must withstand high forces. To accurately predict the response of casings assembly, the non-linear behavior of the casing joints must be considered. Currently, aero-engine manufacturers (i.e PWC) are facing serious limitations in matching the experimental results with FE models prediction tools of the aero-engine.

Feasibility Study of Switch Module Redesign

Structural and vibration analysis is performed on a proposed design change on electronic assembly to ensure that it meets customer requirements and is a more cost-effective design. Such design change should be cost efficient. The important aspect, in addition to the design, is interacting with different engineers at different positions in the company. Working with mechanical engineers and suppliers in achieving such targets and ensuring the work done is viable and on track.

System Controller – Connector/Harness/Baseplate Redesign Feasibility Study

Electronic assemblies are used to control various systems in an aircraft. Under normal operating conditions, these assemblies undergo vibration, and therefore have an expected life span. Different designs are analyzed to reduce production cost, and these designs have to ensure that the electronic components contained within the hardware can tolerate the same operating conditions without failure. With time continuous research projects are being conducted to produce products with the same quality and lower costs, and this is one of them.

Validation and calibration of Squeeze Film Damper Model with Experiment

This research project studies a specific component in the commercial aircraft engine called the squeezed film damper, or SFD. The SFD is applied to reduce the vibration of the engine rotor, which in turn reduces the noise and brings comfort to the passengers. The expected delivery from this project includes an advanced SFD model which will be used by P&WC for the simulation of engine vibration. The developed model can also be studied as the guideline for an upgraded level of SFD design.

Testing nutrient profiling tools and portion size based initiatives (education, regulation and reformulation) for public health policy in Canada

Poor diet is one of the factors associated with obesity and overweight, which may increase the risk for chronic diseases such as diabetes, heart disease and cancer. Two ways to improve the diets at the population level are to 1) establish public health initiatives (e.g.

High energy density lithium ion cells/batteries with excellent electrochemical performance and safety - Year two

Li-ion batteries (LIBs) are currently the most important power source for a wide variety of applications such as cell phones, laptops, computers and other portable electronics. They are also considered as very promising storage/power systems for future electric/hybrid-electric powered transportation. Although clever cell design and improvements in cell subcomponents can bear potential for volume and weight reduction, major developments in high energy density cathode and anode active materials are essential.

Development of Li-Ion cells/batteries for low temperature applications - Year two

Rechargeable lithium-ion batteries are the leading candidate for powering hybrid electric vehicles (HEVs) and pure electric vehicles (EVs) due to their high energy density properties compared to other battery technologies. However, their performance is substantially reduced at temperatures below 0 °C, posing a technical barrier for market penetration of HEVs and EVs. The root cause behind this poor outcome is largely attributed to low conductivity of the electrolyte as well as low lithium-ion diffusivity.

Development and Evaluation of a Life Threatening Infections Point-of-Care Triage Test for the Fionet System - Year two

Febrile syndromes are among the most common causes of global illness accounting for approximately two billion episodes annually. However, most infections are self-limited and only rarely do they progress to critical illness. Our current inability to rapidly identify the small proportion of individuals who will progress to life-threatening infections (LTIs) is a major barrier to effective triage and precision management of serious infections. Our research has identified biomarkers with high diagnostic accuracy for LTIs.

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