Anti-viral potential of polyphenolic compounds isolated from marine seaweeds; multi-target approach against RNA viruses.

This research builds upon previous research performed by the intern regarding identifying natural compounds to inhibit SARS-CoV-2 replication and survival in the host cell. RNA viruses are responsible for notable human diseases, and continuous mutations of these viruses are challenging to develop anti-viral agents. Scientists have developed various anti-viral agents against RNA viruses. However, most are synthetic medications with a narrow spectrum and numerous side effects. Therefore, developing anti-viral medicines by employing natural products which are safer than synthetic compounds can solve these effects. Marine seaweeds generate various polyphenolic compounds for survival due to exposure to extreme conditions. Therefore, these polyphenolic compounds consist of remarkable biological activities against many diseases. Therefore, the proposed research hypothesizes a multi-target approach of polyphenolic compounds isolated from marine seaweeds against RNA viruses by inhibiting viral cell entry mechanism, replication, and survival in the host cell through different therapeutic drug targets can successfully inhibit RNA viral diseases.

Faculty Supervisor:

Isabel Desgagné-Penix

Student:

Partner:

Jeju National University;University of Copenhagen

Discipline:

Life Sciences

Sector:

Education

University:

Université du Québec à Trois-Rivières

Program: