Bioprinting an implantable knee meniscus

Each knee contains two menisci, crescent-shaped pieces of cartilage that play a crucial role in absorbing shock and providing nutrition to the joint. The meniscus is one of the most commonly damaged areas of the knee, unfortunately the body cannot easily repair meniscal injuries, leaving patients with reduced mobility and severe pain. Surgical removal of all or part of the damaged meniscus relieves acute pain, but often leads to osteoarthritis (OA) of the knee. Meniscus implants are a potential solution, however none of the currently available replacements prevent the development of OA.
Bioprinting is the fabrication of 3D structures from biocompatible materials. In this project, we will use novel bioprinting methods to build biocompatible meniscus-like tissues and validate their suitability for surgical implantation into the knee. Success of this project will enable Aspect (partner organisation) to progress to the next phase of meniscus implant development by testing printed tissues in animal models.

Faculty Supervisor:

T. Michael UnderHill

Student:

Partner:

Aspect Biosystems Ltd

Discipline:

Life Sciences

Sector:

Professional, scientific and technical services

University:

The University of British Columbia

Program: