Development of a new generation of neurovascular device for the treatment of fusiform cerebral bifurcation aneurysms using CFD modeling and virtual simulation of stent crimping into a catheter

Cerebral aneurysm (CA), is an abnormal dilation of the cerebral arterial wall, which accounts for more than half a million deaths each year worldwide. Flow diverters (FDs) represent one method recently developed in treating CAs. Typically, they do not need coiling (releasing platinum micro-coils within the aneurysm) and act purely to prevent substantial blood inflow into the aneurysm.In a collaborative project between Biological Multiphysics Research Lab and Composites Research Network at UBC and Evasc Medical System Inc., whose area of expertise is developing novel CA therapies, we plan to develop a novel FD for the treatment of bifurcation CAs with fusiform-like pathology. Through a stepwise design modification process and utilizing CFD modeling, we aim to develop a new design for the Evasc FD (eCLIPs) with improved hemodynamics for such complex CAs. We also plan to develop a novel FEA platform to virtually model the crimping process of the new FD into a catheter. Results of this project will lead to the development of a new generation of neurovascular FDs, which may represent the only device available for the treatment of such CAs with fusiform pathology, and will increase Canada’s presence as a world leader in healthcare technologies.

Faculty Supervisor:

Dana Grecov;Abbas Sadeghzadeh Milani

Student:

Mehdi Jahandardoost

Partner:

eVasc Neurovascular

Discipline:

Engineering - mechanical

Sector:

Professional, scientific and technical services

University:

Program: