Elucidation of candida and human cancer cell (host-pathogen) interaction

Candida is one of the most common fungal pathogens in humans. Through the control of our immune system, Candida resides as a harmeless commensal organism in almost all humans (host). A change in environmental and host conditions leads to Candida changing from its harmless state to a parasitic (pathogenic) state, which causes disease. Candida has the ability to spread through the bloodstream, for example from implanted medical devices, move from the gut during surgery and colonize internal organs in the human body, causing life-threatening infections of the skin, mucosa. Individuals with a weak immune system such as those with acquired immunodeficiency syndrome (AIDS) and cancer are particularly susceptible. The infection caused by Candida, called candidiasis, has high morbidity rates. Although there is an increased risk of developing Candida infections in cancer patients, Candida can also lead to cancer. TO BE CONT’D

Faculty Supervisor:

Tanya Dahms

Student:

Partner:

Université de Toulouse

Discipline:

Life Sciences

Sector:

Education

University:

University of Regina

Program:

Globalink Research Award

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