Functional correlates of central disorders of hypersomnia: a global multi-cohort analysis

The proposed project aims to identify functional brain differences between people with different types of central disorders of hypersomnolence (narcolepsy type 1, narcolepsy type 2, and idiopathic hypersomnia) By combining data from over 1,800 participants from research sites across 21 countries, the project will reveal key brain differences that enhance our understanding of the underlying mechanisms of these disorders. With current diagnostic criteria falling short, this research addresses the urgent need for novel, non-invasive biomarkers that could improve diagnosis and support the development of targeted treatments. The intern will bring valuable expertise in setting up a large-scale MRI analysis to Concordia. She will refine the analysis method and will develop a user-friendly manual that will be used by researchers worldwide. Building on the existing partnership between Concordia and Amsterdam UMC, the project will foster closer collaboration and is expected to lead to high-impact joint publications. Ultimately, it will help position Canada at the forefront of innovative, multi-site neuroimaging research, while strengthening international ties with leading research teams worldwide.

Faculty Supervisor:

Thien Thanh Dang-Vu

Student:

Partner:

Amsterdam UMC

Discipline:

Life Sciences

Sector:

Health and Related Sciences & Technology; Life Sciences (not health)

University:

Concordia University

Program: