Investigating the Effects of High-Intensity Interval Training Based Multimodal Prehabilitation on Inflammatory and Immune Markers in Patients with Non-Metastatic Non-Small Cell Lung Carcinoma – A feasibility study

Lung cancer is a significant health concern worldwide, and a common type called non-small cell lung carcinoma (NSCLC) is responsible for many cases. Surgery is the preferred treatment for early-stage NSCLC, but it can lead to complications after the operation, affecting patient recovery. In addition, inflammation before surgery has been linked to worse outcomes in NSCLC patients. Multimodal prehabilitation programs have emerged as a promising strategy to optimize patient health prior to surgery, potentially improving surgical recovery and reducing complications. Additionally, high-intensity interval training (HIIT) has been effective in reducing post operative complications and inflammatory markers in other conditions but its effects on NSCLC remain unknown. This feasibility study aims to investigate the effects of a supervised 4-week multimodal prehabilitation program, combining HIIT exercise, nutritional support, and psychological support on functional capacity, postoperative complication and inflammatory markers in patients with NSCLC.

Faculty Supervisor:

Jonathan Cools-Lartigue

Student:

Partner:

Peri Operative Program

Discipline:

Life Sciences

Sector:

Health and Related Sciences & Technology

University:

Research Institute of the McGill University Health Centre

Program: