Arthritis is a debilitating disorder characterized by chronic inflammation and persistent pain. This project aims to uncover ways of reducing the pain and discomfort felt by people afflicted by this disorder. A number of key points will be addressed through this project. Firstly, we will gain a better understanding of the possible neurological component in arthritis. Secondly, we will determine if modulating nerve growth factor effects pain in an animal model of arthritis. If it does, we will determine if nerve growth factor can be manipulated in such a way as to be well tolerated.
Dr. Alfredo Ribeiro-da Silva
Pfizer Canada Inc.
Pharmacy / Pharmacology
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