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The current COVID-19 pandemic urgently calls for vaccines able to be rolled out on a global scale. This proposal aims to develop nanoparticle-based vaccine delivery vehicles that can enhance vaccination programs by improving vaccine storage and transport without need for refrigeration, as well as enhance the actual performance of the antigen, a protein found on the Sars-CoV-2 virus surface, in eliciting formation of neutralizing antibodies that protect against serious infection. These delivery vehicles are based on novel, responsive polymers able to enhance storage, delivery and action of the antigen.
Alison Holloway
Roopali Chaudhary
Allarta Life Science Inc
Biology
Manufacturing
McMaster University
Accelerate
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